Mass spectrometric imaging for biomedical tissue analysis

K Chughtai, RMA Heeren - Chemical reviews, 2010 - ACS Publications
A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

MALDI imaging of lipid biochemistry in tissues by mass spectrometry

KA Zemski Berry, JA Hankin, RM Barkley… - Chemical …, 2011 - ACS Publications
As a result of recent advances, remarkable images revealing the distribution of complex
lipids in tissues are now generated by matrix-assisted laser desorption/ionization imaging …

A concise review of mass spectrometry imaging

ERA van Hove, DF Smith, RMA Heeren - Journal of chromatography A, 2010 - Elsevier
Mass spectrometric imaging allows the investigation of the spatial distribution of molecules
at complex surfaces. The combination of molecular speciation with local analysis renders a …

Advances in mass spectrometry for lipidomics

SJ Blanksby, TW Mitchell - Annual Review of Analytical …, 2010 - annualreviews.org
Recent expansion in research in the field of lipidomics has been driven by the development
of new mass spectrometric tools and protocols for the identification and quantification of …

Sample preparation for mass spectrometry imaging: small mistakes can lead to big consequences

RJA Goodwin - Journal of proteomics, 2012 - Elsevier
Mass spectrometry imaging (MSI) enables the direct analysis of molecules from the surface
of a wide variety of samples, allowing the multiplex measurement of both abundance and …

Sample preparation for mass spectrometry imaging of plant tissues: a review

Y Dong, B Li, S Malitsky, I Rogachev… - Frontiers in plant …, 2016 - frontiersin.org
Mass spectrometry imaging (MSI) is a mass spectrometry based molecular ion imaging
technique. It provides the means for ascertaining the spatial distribution of a large variety of …

Molecular imaging by mass spectrometry—looking beyond classical histology

K Schwamborn, RM Caprioli - Nature Reviews Cancer, 2010 - nature.com
Imaging mass spectrometry (IMS) using matrix-assisted laser desorption ionization (MALDI)
is a new and effective tool for molecular studies of complex biological samples such as …

Mass spectrometry imaging and its application in pharmaceutical research and development: A concise review

JG Swales, G Hamm, MR Clench… - International Journal of …, 2019 - Elsevier
Understanding the biodistribution, metabolism and accumulation of drugs in the body is a
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …

Use of mass spectrometry for imaging metabolites in plants

YJ Lee, DC Perdian, Z Song, ES Yeung… - The Plant …, 2012 - Wiley Online Library
We discuss and illustrate recent advances that have been made to image the distribution of
metabolites among cells and tissues of plants using different mass spectrometry …

Lipid imaging by mass spectrometry–a review

D Gode, DA Volmer - Analyst, 2013 - pubs.rsc.org
Mass spectrometry imaging (MSI) has proven to be extremely useful for applications such as
the spatial analysis of peptides and proteins in biological tissue, the performance …