Gut microbiota in human metabolic health and disease

Y Fan, O Pedersen - Nature Reviews Microbiology, 2021 - nature.com
Observational findings achieved during the past two decades suggest that the intestinal
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …

Gut microbiome composition in obese and non-obese persons: a systematic review and meta-analysis

M Pinart, A Dötsch, K Schlicht, M Laudes, J Bouwman… - Nutrients, 2021 - mdpi.com
Whether the gut microbiome in obesity is characterized by lower diversity and altered
composition at the phylum or genus level may be more accurately investigated using high …

Host variables confound gut microbiota studies of human disease

I Vujkovic-Cvijin, J Sklar, L Jiang, L Natarajan, R Knight… - Nature, 2020 - nature.com
Low concordance between studies that examine the role of microbiota in human diseases is
a pervasive challenge that limits the capacity to identify causal relationships between host …

Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders

A Metwaly, S Reitmeier, D Haller - Nature reviews Gastroenterology & …, 2022 - nature.com
The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …

The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk

DD Wang, LH Nguyen, Y Li, Y Yan, W Ma, E Rinott… - Nature medicine, 2021 - nature.com
To address how the microbiome might modify the interaction between diet and
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …

[PDF][PDF] Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course

X Zhou, R Baumann, X Gao, M Mendoza, S Singh… - Cell, 2022 - cell.com
Changes in gut microbiota have been associated with several diseases. Here, the
International Multiple Sclerosis Microbiome Study (iMSMS) studied the gut microbiome of …

[HTML][HTML] The links between gut microbiota and obesity and obesity related diseases

J Geng, Q Ni, W Sun, L Li, X Feng - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The obesity epidemic has become a global public health crisis in recent years and is
continuing to worsen at an alarming rate. However, the pathophysiological mechanisms …

Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals

F Asnicar, SE Berry, AM Valdes, LH Nguyen… - Nature medicine, 2021 - nature.com
The gut microbiome is shaped by diet and influences host metabolism; however, these links
are complex and can be unique to each individual. We performed deep metagenomic …

Metabolism and metabolic disorders and the microbiome: the intestinal microbiota associated with obesity, lipid metabolism, and metabolic health—pathophysiology …

J Aron-Wisnewsky, MV Warmbrunn, M Nieuwdorp… - Gastroenterology, 2021 - Elsevier
Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …

Gut microbiota and BMI throughout childhood: the role of firmicutes, bacteroidetes, and short-chain fatty acid producers

TA Houtman, HA Eckermann, H Smidt, C de Weerth - Scientific reports, 2022 - nature.com
Childhood obesity is a risk factor for numerous health conditions. A critical factor in the
etiology of obesity appears to be the gut microbiota, which is the microbial community that …