Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
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CRISPR-based genome modification and regulation
F Chen, GD Davis - US Patent 10,731,181, 2020 - Google Patents
The present invention provides RNA-guided endonucleases, which are engineered for
expression in eukaryotic cells or embryos, and methods of using the RNA-guided …
expression in eukaryotic cells or embryos, and methods of using the RNA-guided …
Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence
and, together with a modifying polypeptide, provides for site-specific modification of a target …
and, together with a modifying polypeptide, provides for site-specific modification of a target …
Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing
JK Joung, JD Sander, M Maeder, Y Fu - US Patent 9,567,604, 2017 - Google Patents
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Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
JK Joung, S Tsai - US Patent 9,567,603, 2017 - Google Patents
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Compositions and methods of nucleic acid-targeting nucleic acids
AP May, RE Haurwitz, JA Doudna… - US Patent App. 14 …, 2014 - Google Patents
2014-11-06 Assigned to CARIBOU BIOSCIENCES, INC. reassignment CARIBOU
BIOSCIENCES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
BIOSCIENCES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
CRISPR-related methods and compositions with governing gRNAS
F Zhang, D Palestrant, B Davidson, J Mata-Fink… - US Patent …, 2017 - Google Patents
US9834791B2 - CRISPR-related methods and compositions with governing gRNAS -
Google Patents US9834791B2 - CRISPR-related methods and compositions with …
Google Patents US9834791B2 - CRISPR-related methods and compositions with …
Methods and compositions for sequence guiding Cas9 targeting
R Barrangou, KM Selle, AE Briner - US Patent 10,787,654, 2020 - Google Patents
US10787654B2 - Methods and compositions for sequence guiding Cas9 targeting - Google
Patents US10787654B2 - Methods and compositions for sequence guiding Cas9 targeting …
Patents US10787654B2 - Methods and compositions for sequence guiding Cas9 targeting …
Increasing specificity for RNA-guided genome editing
JK Joung, J Angstman, JD Sander, M Maeder… - US Patent …, 2018 - Google Patents
US9885033B2 - Increasing specificity for RNA-guided genome editing - Google Patents
US9885033B2 - Increasing specificity for RNA-guided genome editing - Google Patents …
US9885033B2 - Increasing specificity for RNA-guided genome editing - Google Patents …
RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
JK Joung, M Maeder - US Patent 10,760,064, 2020 - Google Patents
BACKGROUND Clustered Regulatory Interspaced Short Palindromic Repeats (CRISPR),
and CRISPR-associated (cas) genes, referred to as CRISPR/Cas systems, are used by …
and CRISPR-associated (cas) genes, referred to as CRISPR/Cas systems, are used by …