There is an increasing number of neurologic disorders found to be associated with loss
and/or dysfunction of the CNS myelin sheath, ranging from the classic demyelinating …

Diffusible and substratum-bound molecules regulate development and regeneration of the
peripheral nervous system. The understanding of physiological function of these factors …

This study takes advantage of fibroblast growth factor 2 (FGF2) knock-out mice to determine
the contribution of FGF2 to the regeneration of oligodendrocytes in the adult CNS. The role …

Abstract Fibroblast growth factor 2 (FGF2) is an excellent candidate to regulate
remyelination based on its proposed actions in oligodendrocyte lineage cell development in …

Basic fibroblast growth factor (FGF‐2) is expressed in the peripheral nervous system and is
up‐regulated after nerve lesion. It has been demonstrated that administration of FGF‐2 …

The in vivo effects of fibroblast growth factor‐2 (FGF‐2) and insulin‐like growth factor‐I (IGF‐
I) on oligodendrocytes and CNS myelination were determined in the postnatal rat anterior …

Cloning of the fibroblast growth factor receptor (FGFR) adaptor Snt-2 cDNA and the
identification of FGFR-1 protein in association with sperm tails, suggested that FGFR-1 …

To characterize the role of epidermal growth factor (EGF) and fibroblast growth factor (FGF)
in regulating neuroepithelial stem cells differentiation, we have examined the expression of …

Fibroblast growth factors are a family of broad-spectrum growth factors influencing a
plethora of cellular activities. The interaction of at least 23 ligands, 4 receptors and multiple …

Abstract Fibroblast growth factor 2 (FGF2) inhibits oligodendrocyte progenitor cell (OPC)
differentiation during development and limits remyelination following chronic demyelination …