[HTML][HTML] Biophysical insights into modulating lipid digestion in food emulsions

A Acevedo-Fani, H Singh - Progress in lipid research, 2022 - Elsevier
During the last decade, major scientific advances on understanding the mechanisms of lipid
digestion and metabolism have been made, with a view to addressing health issues (such …

Research progress on liposomes: Application in food, digestion behavior and absorption mechanism

W Liu, Y Hou, Y Jin, Y Wang, X Xu, J Han - Trends in Food Science & …, 2020 - Elsevier
Background The application of liposomal system in food area allowing carried and
controlled bioactive-molecules release has been considered one of the main strategies …

Strategies to address low drug solubility in discovery and development

HD Williams, NL Trevaskis, SA Charman… - Pharmacological …, 2013 - Elsevier
Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

50 years of oral lipid-based formulations: provenance, progress and future perspectives

OM Feeney, MF Crum, CL McEvoy, NL Trevaskis… - Advanced drug delivery …, 2016 - Elsevier
Lipid based formulations (LBF) provide well proven opportunities to enhance the oral
absorption of drugs and drug candidates that sit close to, or beyond, the boundaries of …

Self-Assembly of block copolymers into internally ordered microparticles

CK Wong, X Qiang, AHE Müller, AH Gröschel - Progress in Polymer …, 2020 - Elsevier
Block copolymer (BCP) self-assembly is one of the most versatile concepts for the bottom-up
design of functional nanostructures in materials science, nanomedicine and …

[图书][B] Food emulsions: principles, practices, and techniques

DJ McClements - 2004 - taylorfrancis.com
Food Emulsions: Principles, Practice, and Techniques, Second Edition introduces the
fundamentals of emulsion science and demonstrates how this knowledge can be applied to …

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

CJH Porter, NL Trevaskis, WN Charman - Nature reviews Drug …, 2007 - nature.com
Highly potent, but poorly water-soluble, drug candidates are common outcomes of
contemporary drug discovery programmes and present a number of challenges to drug …

Cubosomes in drug delivery—a comprehensive review on its structural components, preparation techniques and therapeutic applications

D Sivadasan, MH Sultan, SS Alqahtani, S Javed - Biomedicines, 2023 - mdpi.com
Cubosomes are lipid vesicles that are comparable to vesicular systems like liposomes.
Cubosomes are created with certain amphiphilic lipids in the presence of a suitable …

Review of in vitro digestion models for rapid screening of emulsion-based systems

DJ McClements, Y Li - Food & function, 2010 - pubs.rsc.org
There is increasing interest in understanding and controlling the digestion of emulsified
lipids within the food and pharmaceutical industries. Emulsion-based delivery systems are …

Enhancing intestinal drug solubilisation using lipid-based delivery systems

CJH Porter, CW Pouton, JF Cuine… - Advanced drug delivery …, 2008 - Elsevier
Lipid-based delivery systems are finding increasing application in the oral delivery of poorly
water-soluble, lipophilic drugs. Whilst lipidic dose forms may improve oral bioavailability via …