Electron microscopy of nanoemulsions: An essential tool for characterisation and stability assessment

V Klang, NB Matsko, C Valenta, F Hofer - Micron, 2012 - Elsevier
The characterisation of pharmaceutical formulations by microscopic techniques is essential
to obtain reliable data about the actual morphology of the system. Since the size range of …

Solid lipid nanoparticles as delivery systems for bioactive food components

J Weiss, EA Decker, DJ McClements, K Kristbergsson… - Food biophysics, 2008 - Springer
The inclusion of bioactive compounds, such as carotenoids, omega-3 fatty acids, or
phytosterols, is an essential requisite for the production of functional foods designed to …

Preparation, characterization and biocompatibility studies on risperidone-loaded solid lipid nanoparticles (SLN): high pressure homogenization versus ultrasound

AC Silva, E González-Mira, ML García, MA Egea… - Colloids and Surfaces B …, 2011 - Elsevier
The suitability of solid lipid nanoparticles (SLN) for the encapsulation of risperidone (RISP),
an antipsychotic lipophilic drug, was assessed for oral administration. The hot high pressure …

[HTML][HTML] Impact of process parameters in the generation of novel aspirin nanoemulsions–comparative studies between ultrasound cavitation and microfluidizer

SY Tang, P Shridharan, M Sivakumar - Ultrasonics sonochemistry, 2013 - Elsevier
In the present investigation, the operating efficiency of a bench-top air-driven microfluidizer
has been compared to that of a bench-top high power ultrasound horn in the production of …

Toxicological considerations when creating nanoparticle-based drugs and drug delivery systems

A Sharma, SRV Madhunapantula… - Expert opinion on drug …, 2012 - Taylor & Francis
Introduction: The biggest challenge faced by the scientific community involved in drug
development is to deliver safe and effective dosage of drugs without causing systemic …

Impact of surfactant properties on oxidative stability of β-carotene encapsulated within solid lipid nanoparticles

T Helgason, TS Awad, K Kristbergsson… - Journal of agricultural …, 2009 - ACS Publications
The impact of surfactant type on the physical and chemical stability of solid lipid nanoparticle
(SLN) suspensions containing encapsulated β-carotene was investigated. Oil-in-water …

High melting lipid based approach for drug delivery: Solid lipid nanoparticles

S Kumar, JK Randhawa - Materials Science and Engineering: C, 2013 - Elsevier
Poor solubility of newly developed drug molecules is the main problem in recent drug
discovery research, so novel drug delivery approaches are being used to deliver these …

Preparation and characterization of solid lipid nanoparticles-a review

R Parhi, P Suresh - Current drug discovery technologies, 2012 - ingentaconnect.com
In the present scenario, most of the developed and new discovered drugs are posing real
challenge to the formulation scientists due to their poor aqueous solubility which in turn is …

Lipid based nanocarrier system for the potential oral delivery of decitabine: formulation design, characterization, ex vivo, and in vivo assessment

YR Neupane, M Srivastava, N Ahmad, N Kumar… - International journal of …, 2014 - Elsevier
The aim of this study was to design and fabricate nanostructured lipid carrier (NLC) for the
potential oral delivery of decitabine (DCB). NLC was prepared by cold homogenization …

Recent advances and patents on solid lipid nanoparticles

KK Sawant, SS Dodiya - Recent patents on drug delivery & …, 2008 - ingentaconnect.com
Solid Lipid Nanoparticles (SLNs) have attracted increasing scientific and commercial
attention as colloidal drug carriers during the last decade. They have emerged as a potential …