Autism spectrum disorder at the crossroad between genes and environment: contributions, convergences, and interactions in ASD developmental pathophysiology

C Cheroni, N Caporale, G Testa - Molecular autism, 2020 - Springer
The complex pathophysiology of autism spectrum disorder encompasses interactions
between genetic and environmental factors. On the one hand, hundreds of genes …

Recent progress in translational engineered in vitro models of the central nervous system

P Nikolakopoulou, R Rauti, D Voulgaris, I Shlomy… - Brain, 2020 - academic.oup.com
The complexity of the human brain poses a substantial challenge for the development of
models of the CNS. Current animal models lack many essential human characteristics (in …

Methylmercury and brain development: A review of recent literature

AA Dos Santos, MA Hort, M Culbreth… - Journal of trace …, 2016 - Elsevier
Methylmercury (MeHg) is a potent environmental pollutant, which elicits significant toxicity in
humans. The central nervous system (CNS) is the primary target of toxicity, and is …

[HTML][HTML] Food for Thought…: Developmental Neurotoxicity–Challenges in the 21st Century and In Vitro Opportunities

L Smirnova, HT Hogberg, M Leist, T Hartung - Altex, 2014 - ncbi.nlm.nih.gov
In recent years neurodevelopmental problems in children have increased at a rate that
suggests lifestyle factors and chemical exposures as likely contributors. When …

Food contaminants: Impact of food processing, challenges and mitigation strategies for food security

A Vignesh, TC Amal, K Vasanth - Food Research International, 2024 - Elsevier
Food preparation involves the blending of various food ingredients to make more convenient
processed food products. It is a long chain process, where each stage posing a risk of …

Comparability of behavioural assays using zebrafish larvae to assess neurotoxicity

J Legradi, N El Abdellaoui, M Van Pomeren… - … Science and Pollution …, 2015 - Springer
Testing of compounds for neurotoxicity has become increasingly important in recent years. It
has been shown that neurological disorders like autism may be related to chemical …

[HTML][HTML] Impact of environmentally relevant concentrations of fluoxetine on zebrafish larvae: from gene to behavior

D Correia, M Bellot, E Prats, C Gómez-Canela, H Moro… - Chemosphere, 2023 - Elsevier
Fluoxetine is widely prescribed for the treatment of depressive states, acting at the level of
the central nervous system, consequently affecting non-target organisms. This study aimed …

[图书][B] Psychology for sustainability

BA Scott, EL Amel, CM Manning - 2021 - taylorfrancis.com
Psychology for Sustainability applies psychological science to so-called environmental
problems that manifest when human behavior disrupts and degrades natural systems …

Expanding the test set: Chemicals with potential to disrupt mammalian brain development

WR Mundy, S Padilla, JM Breier, KM Crofton… - Neurotoxicology and …, 2015 - Elsevier
High-throughput test methods including molecular, cellular, and alternative species-based
assays that examine critical events of normal brain development are being developed for …

Neuronal development and axon growth are altered by glyphosate through a WNT non-canonical signaling pathway

RP Coullery, ME Ferrari, SB Rosso - Neurotoxicology, 2016 - Elsevier
The growth and morphological differentiation of neurons are critical events in the
establishment of proper neuronal connectivity and functioning. The developing nervous …