Extracellular vesicles (EVs) represent a novel mechanism of intercellular communication as
vehicles for intercellular transfer of functional membrane and cytosolic proteins, lipids, and …

Cell-surface proteins of the tetraspanin family are small, and often hidden by a canopy of tall
glycoprotein neighbours in the cell membrane. Consequently, tetraspanins have been …

The extracellular matrix (ECM) is critical for all aspects of vascular biology. In concert with
supporting cells, endothelial cells (ECs) assemble a laminin-rich basement membrane …

▪ Abstract This review summarizes key aspects of tetraspanin proteins, with a focus on the
functional relevance and structural features of these proteins and how they are organized …

Tumours progress through a cascade of events that enable the formation of metastases.
Some of the components that are required for this fatal process are well established …

Despite high expression levels at the plasma membrane or in intracellular vesicles,
tetraspanins remain among the most mysterious transmembrane molecules 20 years after …

Exciting new findings have emerged about the structure, function and biochemistry of
tetraspanin proteins. Five distinct tetraspanin regions have now been delineated linking …

The tetraspanin transmembrane proteins have emerged as key players in malignancy, the
immune system, during fertilization and infectious disease processes. Tetraspanins engage …

Relatively little attention has been given to the large family of abundantly expressed
transmembrane proteins known as tetraspanins. Now, the importance of tetraspanins is …

Here we demonstrate that multiple tetraspanin (transmembrane 4 superfamily) proteins are
palmitoylated, in either the Golgi or a post-Golgi compartment. Using CD151 as a model …