In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …

Cancer is known as one of the main causes of death in the world; and many compounds
have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile …

Drug sensitivity and resistance testing on diagnostic leukemia samples should provide
important functional information to guide actionable target and biomarker discovery. We …

Src kinase (Src) is a tyrosine protein kinase that regulates cellular metabolism, survival, and
proliferation. Many studies have shown that Src plays multiple roles in macrophage …

Currently, cancer and its progression to metastasis result in a large number of deaths. The
lack of new drugs, appropriate clinical trials for metastasis preventive drugs and incomplete …

The increasing demand for new bioactive compounds to combat the evolution of multi-drug
resistance (MDR) requires research on microorganisms in different environments in order to …

Targeting CD96 that originates in immune cells has shown potential for cancer therapy.
However, the role of intrinsic CD96 in solid tumor cells remains unknown. Here, it is found …

Abstract Knowledge of the molecular events that contribute to prostate cancer progression
has created opportunities to develop novel therapy strategies. It is now well established that …

Background: Metastasis accounts for the high lethality of colorectal cancer (CRC) patients.
Unfortunately, the molecular mechanism manipulating metastasis in CRC is still elusive …

Actinic keratosis (AK) is among the most commonly diagnosed skin diseases with potentially
life-threatening repercussions if left untreated. Usage of pharmacologic agents represents …