The tumor development and metastasis are closely related to the structure and function of
the tumor microenvironment (TME). Recently, TME modulation strategies have attracted …

Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …

Abstract Traditional Chinese Medicine (TCM) has the characteristics of multiple targets,
slight side effects and good therapeutic effects. Good anti-tumor effects are shown by …

Autophagy is a highly conserved catabolic process and participates in a variety of cellular
biological activities. The phosphoinositide 3-kinase (PI3K)/protein kinase B …

Cancer is characterized by increased oxidative stress, an imbalance between reactive
oxygen species (ROS) and antioxidants. Enhanced ROS accumulation, as a result of …

Ovarian cancer is one of the leading causes of death in patients with gynecological
malignancy. Despite optimal cytoreductive surgery and platinum-based chemotherapy …

Wound healing is one of the major global health concerns in patients with diabetes.
Overactivation of pro-inflammatory M1 macrophages is associated with delayed wound …

Hypoxic tumor microenvironment is a common feature of solid tumors and is associated with
aggressiveness and poor patient outcomes. A continuous interference between cancer cells …

The human gut microbiota is a complex ecosystem involved in the metabolism, immunity,
and health of the host. The microbiome plays a key role in the development of the host's …

The tumor microenvironment (TME) is a complex ecosystem, which includes many different
types of cells, abnormal vascular systems, and immunosuppressive cytokines. TME serves …