The successful delivery of drugs across the oral mucosa represents a continuing challenge,
as well as a great opportunity. Oral transmucosal delivery, especially buccal and sublingual …

Orally disintegrating tablets (ODTs), also known as fast melts, quick melts, fast disintegrating
and orodispersible systems, have the unique property of disintegrating in the mouth in …

Solubility of curcumin at physiological pH was significantly increased by forming solid
dispersion (SD) with Solutol® HS15. Since curcumin undergoes hydrolytic degradation …

Nisoldipine is a calcium channel blocker with low and variable oral bioavailability. This was
attributed to slow dissolution and presystemic metabolism. Accordingly, the objective of this …

Solubility is an important determinant in drug liberation and hence drug absorption, which
plays a key role in oral bioavailability of formulations. The dissolution rate of a drug directly …

The aim of the present study is to monitor the release of perphenazine (PPZ) from thin
polymer films in real-time by the multi-parametric surface plasmon resonance method (MP …

Scrutinizing critical thermodynamic and kinetic factors for glass formation and the glass
stability of materials would benefit the screening of the glass formers for the industry of …

Paracetamol (PCM) is a non-steroidal anti-inflammatory drug (NSAID), sparingly soluble and
bitter in taste. It is widely used as an analgesic and antipyretic. Solid dispersion of drug with …

The aim of this study was to compare the applicability of inulin, its surface-active derivative
(Inutec® SP1), and polyvinylpyrrolidone (PVP) as carriers in high drug load solid …

Amorphous solid dispersions (ASD) stand on the forefront of solubilizing formulations for
many poorly soluble drug candidates. It has been widely accepted that the physical stability …