Transplantation of frozen-thawed ovarian tissue: an update on worldwide activity published in peer-reviewed papers and on the Danish cohort

SE Gellert, SE Pors, SG Kristensen… - Journal of Assisted …, 2018 - Springer
Purpose The purpose of the study is to review all peer-reviewed published reports of women
receiving ovarian tissue transplantation (OTT) with frozen/thawed tissue (OTC) with respect …

[HTML][HTML] Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation

J Donnez, MM Dolmans, A Pellicer, C Diaz-Garcia… - Fertility and sterility, 2013 - Elsevier
Aggressive chemotherapy/radiotherapy and bone marrow transplantation can cure> 90% of
girls and young women affected by disorders requiring such treatment. However, the ovaries …

86 successful births and 9 ongoing pregnancies worldwide in women transplanted with frozen-thawed ovarian tissue: focus on birth and perinatal outcome in 40 of …

AK Jensen, KT Macklon, J Fedder, E Ernst… - Journal of assisted …, 2017 - Springer
Purpose This study aims to make an account of the children born following transplantation of
frozen-thawed ovarian tissue worldwide with specific focus on the perinatal outcome of the …

Primary ovarian insufficiency

M De Vos, P Devroey, BCJM Fauser - The Lancet, 2010 - thelancet.com
Primary ovarian insufficiency is a subclass of ovarian dysfunction in which the cause is
within the ovary. In most cases, an unknown mechanism leads to premature exhaustion of …

Current success and efficiency of autologous ovarian transplantation: a meta-analysis

F Pacheco, K Oktay - Reproductive Sciences, 2017 - journals.sagepub.com
Context: Ovarian cryopreservation followed by autotransplantation is still considered an
experimental strategy for fertility preservation (FP) mainly because the success rates are …

Fertility preservation in women

J Donnez, MM Dolmans - Nature Reviews Endocrinology, 2013 - nature.com
In women,∼ 10% of cancers occur in those< 45 years old. Chemotherapy, radiotherapy and
bone marrow transplantation can cure> 90% of girls and young women with diseases that …

[HTML][HTML] Risk of transferring malignant cells with transplanted frozen-thawed ovarian tissue

MM Dolmans, V Luyckx, J Donnez, CY Andersen… - Fertility and sterility, 2013 - Elsevier
Ovarian tissue cryopreservation and transplantation is a real option to preserve and restore
fertility in young cancer patients. However, there is a concern regarding the possible …

Cryopreservation of human ovarian tissue: a review

EC Rivas Leonel, CM Lucci, CA Amorim - Transfusion medicine and …, 2019 - karger.com
Background: Cryopreservation of human ovarian tissue has been increasingly applied
worldwide to safeguard fertility in cancer patients, notably in young girls and women who …

Reimplantation of cryopreserved ovarian tissue from patients with acute lymphoblastic leukemia is potentially unsafe

MM Dolmans, C Marinescu, P Saussoy… - Blood, The Journal …, 2010 - ashpublications.org
Ovarian tissue cryopreservation is currently proposed to young cancer patients to preserve
their fertility before radiochemotherapy. The potential risk is that the tissue might harbor …

Children born after autotransplantation of cryopreserved ovarian tissue. A review of 13 live births

J Donnez, S Silber, CY Andersen, I Demeestere… - Annals of …, 2011 - Taylor & Francis
Introduction. Premature ovarian failure (POF) can occur naturally at an early age or be due
to iatrogenic agents. Indeed, ovaries are very sensitive to cytotoxic treatment, especially to …