The recent construction of brain-wide gene expression atlases, which measure the transcriptional activity of thousands of genes in multiple anatomical locations, has made it …
During rest, brain activity is synchronized between different regions widely distributed throughout the brain, forming functional networks. However, the molecular mechanisms …
The structure and function of the human brain are highly stereotyped, implying a conserved molecular program responsible for its development, cellular structure and function. We …
The brain is a network of interleaved neural circuits. In modern connectomics, brain connectivity is typically encoded as a network of nodes and edges, abstracting away the rich …
The brain is expensive, incurring high material and metabolic costs for its size—relative to the size of the body—and many aspects of brain network organization can be mostly …
BD Fulcher, A Fornito - … of the National Academy of Sciences, 2016 - National Acad Sciences
Connectivity is not distributed evenly throughout the brain. Instead, it is concentrated on a small number of highly connected neural elements that act as network hubs. Across different …
Human functional magnetic resonance imaging (fMRI) brain networks have a complex topology comprising integrative components, eg long-distance inter-modular edges, that are …
The human isocortex consists of tangentially organized layers with unique cytoarchitectural properties. These layers show spatial variations in thickness and cytoarchitecture across the …
Brain connectomes are topologically complex systems, anatomically embedded in 3D space. Anatomical conservation of “wiring cost” explains many but not all aspects of these …