Macrophages exist in various tissues, several body cavities, and around mucosal surfaces
and are a vital part of the innate immune system for host defense against many pathogens …

Fibrosis is the endpoint of pathological remodeling. This process contributes to the
pathogenesis of several chronic disorders and aging-associated organ damage. Different …

Background Silicosis is one of the most common occupational pulmonary fibrosis caused by
respirable silica-based particle exposure, with no ideal drugs at present. Metformin, a …

Long non-coding RNAs (lncRNAs) are versatile regulators of gene expression and play
crucial roles in diverse biological processes. Epithelial-mesenchymal transition (EMT) is a …

Fibrosis is universally observed in multiple aging-related diseases and progressions and is
characterized by excess accumulation of the extracellular matrix. Fibrosis occurs in various …

Pulmonary fibrosis (PF) is a serious and progressive lung disease which is possibly life-
threatening. It causes lung scarring and affects lung functions including epithelial cell injury …

Abstract Background N 6-methyladenosine (m6A) is the most common and abundant
internal modification of RNA. Its critical functions in multiple physiological and pathological …

Silicosis is a kind of irreversible pulmonary fibrosis induced by the long-term inhalation of
silica particles. The therapeutic strategy based on the microRNAs might be an effective way …

Pulmonary fibrosis is a chronic and progressive fibrotic disease that results in impaired gas
exchange, ventilation, and eventual death. The pro-fibrotic environment is instigated by …

Long non-coding RNAs (lncRNAs) have been reported to be involved in various
pathophysiological processes in many diseases. However, the role and mechanism of …