Primary objective: To determine whether S100B protein in serum can predict intracranial
lesions on computed tomography (CT) scan after mild traumatic brain injury (MTBI) …

Reliable diagnosis of traumatic brain injury (TBI) is a major public health need. Glial fibrillary
acidic protein (GFAP) is expressed in the central nervous system, and breakdown products …

BACKGROUND: Although controversial, failing to consider the gravitational effects of head
elevation on cerebral perfusion is speculated to increase susceptibility to rare, but …

Background. Postoperative cognitive dysfunction (POCD) is common after non-cardiac
surgery, but the mechanism is unclear. We hypothesized that decrements in cognition 1 …

Background Two distinct and large bodies of literature exist on resilience that are of potential
interest for surgical outcomes. First is the literature on the impact of resilience on surgical …

Objectives Delirium is the most common postoperative neurological complication and some
evidence suggests that dexmedetomidine is associated with a decreased incidence of …

Background Individualizing blood pressure targets could improve organ perfusion compared
with current practices. In this study we assess whether hypotension defined by cerebral …

Background Debilitating brain injury occurs in 1.6–5% of patients undergoing cardiac
surgery with cardiopulmonary bypass. Diffusion-weighted magnetic resonance imaging …

Background Rewarming from hypothermia during cardiopulmonary bypass (CPB) may
compromise cerebral oxygen balance, potentially resulting in cerebral ischemia. The …

Objective This study was performed to investigate the correlation among decreased regional
cerebral oxygen saturation (rSO2), blood levels of brain injury biomarkers, and …