Recent discoveries implicate the classical complement cascade in normal brain
development and in disease. Complement proteins C1q, C3, and C4 participate in synapse …

Objectives To describe brain magnetic resonance imaging (MRI) abnormalities in newly
diagnosed neuropsychiatric lupus (NPSLE). To correlate them with clinical and laboratory …

The complement system consists of more than 30 proteins that have long been known to
participate to the immune defence against pathogens and to the removal of damaged cells …

Neurological involvement is considered to be a serious complication of systemic lupus
erythematosus (SLE). Neuroimaging plays an important role in detecting neurological …

We have begun to better understand how brain-reactive autoantibodies, present in a
proportion of SLE patients, can cause brain injury and diffuse NPSLE. Further testing will be …

Purpose Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease
that can affect the central nervous system. Neuropsychiatric symptoms are found in 25–70 …

El lupus eritematoso sistémico es una enfermedad autoinmune, sistémica, caracterizada por
la producción de autoanticuerpos y una amplia diversidad de manifestaciones clínicas …

El lupus eritematoso sistémico es una enfermedad autoinmune, sistémica, caracterizada por
la producción de autoanticuerpos y una diversidad de manifestaciones clínicas entre las …

Objective This study investigated differences in subcortical brain volumes of SLE patients
with cognitive deficits (SLE-CD) and SLE patients with normal cognitive performance (SLE …

The diagnosis and pathology of neuropsychiatric systemic lupus erythematosus (NPSLE)
remains challenging. Herein, we used multimodal imaging to assess anatomical and …