Modulating the activity of androgen receptor for treating breast cancer

CP You, H Tsoi, EPS Man, MH Leung… - International Journal of …, 2022 - mdpi.com
The androgen receptor (AR) is a steroid hormone receptor widely detected in breast cancer.
Evidence suggests that the AR might be a tumor suppressor in estrogen receptor alpha …

[HTML][HTML] An androgen receptor regulated gene score is associated with epithelial to mesenchymal transition features in triple negative breast cancers

S Rajarajan, VP Snijesh, CE Anupama, MG Nair… - Translational …, 2023 - Elsevier
Background Androgen receptor (AR) is considered a marker of better prognosis in hormone
receptor positive breast cancers (BC), however, its role in triple negative breast cancer …

Breast cancers with intermediate Estrogen Receptor expression: Characteristics, prognosis and treatment

IA Voutsadakis - Clinical Breast Cancer, 2024 - Elsevier
In the era of personalized oncology biomarkers that identify subgroups of specific cancers
and help predict response to specific therapies are critical tools for prognosis determination …

Overexpression of BQ323636. 1 contributes to anastrozole resistance in AR+ ve/ER+ ve breast cancer

H Tsoi, J Lok, EPS Man, CN Cheng… - The Journal of …, 2023 - Wiley Online Library
Aromatase inhibitors (Ais) are used as adjuvant endocrine therapy for oestrogen receptor‐
positive (ER+ ve) post‐menopausal breast cancer patients. Ais, by inhibiting the enzyme …

[HTML][HTML] Elucidating Sex-Specific Immune Profiles in a Breast Cancer Model

E Hargrove-Wiley, D Obodo, W Bindeman… - International Journal of …, 2024 - mdpi.com
Breast cancer is commonly thought of as a “women's disease”. However, men are
increasingly diagnosed with the disease, and their mortality rates are disparately higher than …

[HTML][HTML] Differential role of glucocorticoid receptor based on its cell type specific expression on tumor cells and infiltrating lymphocytes

VP Snijesh, VP Nimbalkar, S Patil, S Rajarajan… - Translational …, 2024 - Elsevier
Background The glucocorticoid receptor (GR) is frequently expressed in breast cancer (BC),
and its prognostic implications are contingent on estrogen receptor (ER) status. To address …

Investigation of the relationship between breast cancer and clinical symptoms of polycystic ovarian syndrome: a case-control study

A Hemati, L Amini, S Haghani, EA Hashemi - BMC Women's Health, 2024 - Springer
Background Breast cancer is the most commonly diagnosed cancer among women
worldwide, and it is associated with significant number of metabolic and reproductive risk …

Correlation between Androgen Receptor Expression in Luminal B (HER–2 Negative) Breast Cancer and Disease Outcomes

F Yang, J Li, H Zhang, S Zhang, J Ye, Y Cheng… - Journal of Personalized …, 2022 - mdpi.com
(1) Background: Hormone receptor positive breast cancer is a subtype of breast cancer with
relatively good prognosis, but luminal B (HER–2 negative) breast cancer has a higher risk of …

Meeting proceedings of the 43rd Indian Association for Cancer Research (IACR)

AJ Malik, R Malaviya - 2024 - journals.biologists.com
ABSTRACT The 43rd Annual Conference of the Indian Association of Cancer Research
(IACR) was held between 19th and 22nd January 2024 at the Indian Institute of Education …

[HTML][HTML] Breast cancer relapses considering molecular biological characteristics

II Smolanka, OV Movchan, IY Bagmut… - Journal of Medicine …, 2023 - ncbi.nlm.nih.gov
We aimed to analyze the frequency of breast cancer relapses and their relationship with
molecular and biological tumor characteristics. We studied 6,136 breast cancer patients …