The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

This review will focus on how bile acids are being used in clinical trials to treat neurological
diseases due to their central involvement with the gut-liver-brain axis and their physiological …

The pathoetiology and pathophysiology of motor neuron loss in amyotrophic lateral sclerosis
(ALS) are still to be determined, with only a small percentage of ALS patients having a …

There is a growing body of evidence highlighting there are significant changes in the gut
microbiota composition and relative abundance in various neurological disorders. We …

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The aetiologies and origins of neurodegenerative diseases, such as Alzheimer's disease
(AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and Huntington's …

Amyotrophic lateral sclerosis (ALS) is a complex, fatal neurodegenerative disease. Disease
pathophysiology is incompletely understood but evidence suggests gut dysbiosis occurs in …

Niacin (vitamin B3) is an essential nutrient that treats pellagra, and prior to the advent of
statins, niacin was commonly used to counter dyslipidemia. Recent evidence has posited …

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal
neurodegenerative disorders often co-occurring in the same patient, a feature that suggests …

Amyotrophic lateral sclerosis is a devastating neurodegenerative disease characterized by
the gradual loss of motor neurons in the brain and spinal cord, leading to progressive motor …