Fibroblast growth factor (FGF) 19 and FGF21 are hormones that regulate metabolic
processes particularly during feeding or starvation, thus ultimately influencing energy …

Understanding temperature production and regulation in endotherm organisms becomes a
crucial challenge facing the increased frequency and intensity of heat strokes related to …

Obesity is caused by an imbalance between food intake and energy expenditure (EE). Here
we identify a conserved pathway that links signalling through peripheral Y1 receptors (Y1R) …

Background Osteocytes are the main stress-sensing cells in bone. The substances secreted
by osteocytes under mechanical loading play a crucial role in maintaining body …

Skeletal tissue involves systemic adipose tissue metabolism and energy expenditure.
MicroRNA signaling controls high-fat diet (HFD)-induced bone and fat homeostasis …

Cold temperature activates the sympathetic nervous system (SNS) to induce bone loss by
altering bone remodeling. Brown adipose tissue (BAT) is influenced by the SNS in cold …

Unlocking the therapeutic potential of brown/beige adipose tissue requires technological
advancements that enable the controlled expansion of this uniquely thermogenic tissue …

Recent observations indicate that the cross-sectional area (CSA) of vertebral bodies is on
average 10% smaller in healthy newborn girls than in newborn boys, a striking difference …

Growing female mice housed at room temperature (22° C) weigh the same but differ in body
composition compared to mice housed at thermoneutrality (32° C). Specifically, mice housed …

This study highlights the therapeutic potential of activating brown adipose tissue (BAT) for
managing polycystic ovary syndrome (PCOS), a prevalent endocrine disorder associated …