Designing formulation strategies for enhanced stability of therapeutic peptides in aqueous solutions: A review

PP Nugrahadi, WLJ Hinrichs, HW Frijlink, C Schöneich… - Pharmaceutics, 2023 - mdpi.com
Over the past few decades, there has been a tremendous increase in the utilization of
therapeutic peptides. Therapeutic peptides are usually administered via the parenteral …

[HTML][HTML] Self-emulsifying drug delivery systems (SEDDS): How organic solvent release governs the fate of their cargo

AM Jörgensen, R Wibel, F Veider, B Hoyer… - International Journal of …, 2023 - Elsevier
Organic solvents are commonly used in self-emulsifying drug delivery systems (SEDDS) to
increase payloads of orally administered poorly soluble drugs. Since such solvents are …

Development of Amino Acid-Based Surfactants: From Synthesis to Applications

K Holmberg, F Bilén, R Bordes - Current Opinion in Colloid & Interface …, 2024 - Elsevier
The diversity of both natural and non-natural amino acids provides a strong foundation for
the synthesis of a wide array of surfactants and offers the possibility to control the …

Power-Up for Mucoadhesiveness: Two Generations of Thiolated Surfactants for Enhanced Sticky Nanoemulsions

D To, G Kali, S Haddadzadegan… - ACS Biomaterials …, 2023 - ACS Publications
Nanoemulsions can be tuned toward enhanced gastro-intestinal retention time by
incorporating thiolated surfactants into their surface. Tailoring the chemical reactivity of the …

Histidine-based ionizable cationic surfactants: novel biodegradable agents for hydrophilic macromolecular drug delivery

I Polidori, D To, G Kali, A Bernkop-Schnürch - Drug Delivery and …, 2024 - Springer
The aim of this study was to design surfactants based on histidine (His) for hydrophobic ion-
pairing and evaluate their safety and efficacy. Lauryl, palmitoyl and oleyl alcohol, as well as …

Carboxymethyl chitosan/polyvinyl alcohol hydrogel films by incorporating MSNs as ε-PL carrier with pH-responsive controlled release and antibacterial properties

D Wang, S Fan, X Li, L Chen, X Wen, Y Xu… - Food Packaging and …, 2024 - Elsevier
A hydrogel film with pH-responsive release and excellent antibacterial properties was
developed by utilizing mesoporous silica nanoparticles (MSNs) as carriers for ε-PL …

Comparative Analysis of PEG‐Free and PEG‐Based Self‐Emulsifying Drug Delivery Systems for Enhanced Oral Bioavailability of Therapeutic (Poly) Peptides

S Haddadzadegan, D To, A Matteo Jörgensen, R Wibel… - Small, 2024 - Wiley Online Library
This study aims to compare the potential of Polyethylene glycol (PEG‐free and PEG‐based
self‐emulsifying drug delivery systems (SEDDS) for the oral administration of insulin …

Enhanced phenol removal from aqueous media by adsorption onto organo-modified bentonite

H Alidra, F Djazi, B Keskin - Research on Chemical Intermediates, 2024 - Springer
The removal of organic pollutants from contaminated water was the interest of numerous
research works, which demonstrated the efficiency of adsorption and organo-modified …

Study of organosilicon surfactants against bituminous coal dust: A macro-and microscale multiscale interaction study

W Nie, C Shi, W Niu, Q Bao, R Li, Q Tian… - Chemical Engineering …, 2024 - Elsevier
In this paper, the molecular properties of an organosilicon surfactant (GT-248) were
investigated with macroscopic experiments, simulations of the coupling of a fine droplets of …

[HTML][HTML] The Potential of Colloidal Systems Based on Carbamate-Containing Hexadecylpiperidinium Surfactants in Biomedical Applications

R Kushnazarova, A Mirgorodskaya, D Bekrenev… - Colloids and …, 2024 - mdpi.com
New hexadecylpiperidinium surfactants, containing one or two butylcarbamate fragments,
were synthesized. The antimicrobial activity, toxicity, aggregation behavior in aqueous …