New insights into the pathophysiology and therapeutic targets of asthma and comorbid chronic rhinosinusitis with or without nasal polyposis

I Striz, K Golebski, Z Strizova, S Loukides… - Clinical …, 2023 - portlandpress.com
Asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) or without (CRSsNP) are
chronic respiratory diseases. These two disorders often co-exist based on common …

Genetics and epigenetics of chronic rhinosinusitis

D Lal, T Brar, SP Ramkumar, J Li, A Kato… - Journal of Allergy and …, 2023 - Elsevier
Discerning the genetics and epigenetics of chronic rhinosinusitis (CRS) may optimize
outcomes through early diagnostics, personalized and novel therapeutics, and early …

Current insight into treatment of chronic rhinosinusitis: phenotypes, endotypes, and implications for targeted therapeutics

N Chapurin, J Wu, AB Labby, RK Chandra… - Journal of Allergy and …, 2022 - Elsevier
Chronic rhinosinusitis is characterized by persistent locoregional mucosal inflammation of
the paranasal sinuses and upper airway that has substantial associated health care costs …

Mechanisms and pathogenesis of chronic rhinosinusitis

A Kato, RP Schleimer, BS Bleier - Journal of Allergy and Clinical …, 2022 - Elsevier
Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local
inflammation of the upper airways and is historically divided into 2 main phenotypes: CRS …

Prognostic factors for post-operative outcomes in chronic rhinosinusitis with nasal polyps: a systematic review

S Cai, H Lou, L Zhang - Expert Review of Clinical Immunology, 2023 - Taylor & Francis
Introduction Chronic rhinosinusitis with nasal polyps (CRSwNP) has a high recurrence rate
after surgery despite the availability of medical treatments. Multiple clinical and biological …

[HTML][HTML] The current findings in eosinophilic chronic rhinosinusitis

T Tsuda, M Suzuki, Y Kato, M Kidoguchi, T Kumai… - Auris Nasus …, 2024 - Elsevier
Chronic rhinosinusitis (CRS) is a persistent inflammatory disease of the nasal cavity and
paranasal sinuses. Traditional classification is denoted by the presence (CRSwNP) or …

M2 macrophage-related gene signature in chronic rhinosinusitis with nasal polyps

Y Zhu, X Sun, S Tan, C Luo, J Zhou, S Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common sinonasal
inflammatory disorder with high heterogeneity. Increasing evidence have indicated that the …

Epidemiology and aetiology of chronic rhinosinusitis in Asia—A narrative review

J Chee, KW Pang, T Low, DY Wang… - Clinical …, 2023 - Wiley Online Library
Background Despite having a similar prevalence to Western populations, literature on
chronic rhinosinusitis (CRS) in the Asian population is sparse. There is limited data on the …

Chronic rhinosinusitis with nasal polyps: Key considerations in the multidisciplinary team approach

O Pfaar, AT Peters, C Taillé, T Teeling… - Clinical and …, 2025 - Wiley Online Library
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a recurrent inflammatory
disease associated with several comorbidities and a significant disease burden for patients …

Prevalence and risk factors of chronic rhinosinusitis among Chinese: A systematic review and meta-analysis

L Zhang, R Zhang, K Pang, J Liao, C Liao… - Frontiers in Public …, 2023 - frontiersin.org
Background Chronic rhinosinusitis (CRS) can be seen in people of all ages. CRS heavily
affects the quality of a patient's daily life and also causes tremendous economic burdens on …