Silymarin, a mixture of flavonolignan and flavonoid polyphenolic compounds extractable from milk thistle (Silybum marianum) seeds, has anti-oxidant, anti-inflammatory, anti-cancer …
A Eftekhari, SM Dizaj, L Chodari, S Sunar… - Biomedicine & …, 2018 - Elsevier
Developmental toxicity caused by exposure to a mixture of environmental pollutants has become a major health concern. Human-made chemicals, including xenoestrogens …
AG Grigoras - Environmental Chemistry Letters, 2019 - Springer
Advanced drug delivery systems are now designed with biodegradable, biocompatible and non-toxic materials such as polysaccharides. Pullulan is a polysaccharide consisting of …
Some nano-formulations of silymarin (SM), a drug commonly used for liver diseases, were developed to overcome its poor solubility and poor bioavailability; antifibrotic effect of these …
The objectives of this study were to formulate, characterize silymarin-loaded Eudragit nanoparticles (SNPs) and evaluate their hepatoprotective and cytotoxic effects after oral …
The escalating global burden of tuberculosis necessitates radical strategies to curb its spread. In this study, rifampicin (RIF), a first line anti-tubercular antibiotic and curcumin …
KS Harini, E Devaraj - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
Liver fibrosis remains a life-threatening pathological condition, which might lead to complications like cirrhosis and hepatocellular carcinoma when left untreated. The lack of …
Eudragit-loaded silymarin nanoparticles (SNPs) and their formulation into buccal mucoadhesive tablets were investigated to improve the low bioavailability of silymarin …
In this study, we formulated silymarin-HSA nanoplex and assayed its ability to reduce LPS- induced toxicity in vitro and in vivo. Silymarin molecules were encapsulated into HSA …