The burden of survivors: how can phage infection impact non-infected bacteria?

AV Letarov, MA Letarova - International Journal of Molecular Sciences, 2023 - mdpi.com
The contemporary understanding of complex interactions in natural microbial communities
and the numerous mechanisms of bacterial communication challenge the classical concept …

A growing microcolony can survive and support persistent propagation of virulent phages

RS Eriksen, SL Svenningsen… - Proceedings of the …, 2018 - National Acad Sciences
Bacteria form colonies and secrete extracellular polymeric substances that surround the
individual cells. These spatial structures are often associated with collaboration and quorum …

[HTML][HTML] Phage “delay” towards enhancing bacterial escape from biofilms: a more comprehensive way of viewing resistance to bacteriophages

ST Abedon - AIMS microbiology, 2017 - ncbi.nlm.nih.gov
In exploring bacterial resistance to bacteriophages, emphasis typically is placed on those
mechanisms which completely prevent phage replication. Such resistance can be detected …

Phage-bacterial dynamics with spatial structure: self organization around phage sinks can promote increased cell densities

JJ Bull, KA Christensen, C Scott, BR Jack, CJ Crandall… - Antibiotics, 2018 - mdpi.com
Bacteria growing on surfaces appear to be profoundly more resistant to control by lytic
bacteriophages than do the same cells grown in liquid. Here, we use simulation models to …

In silico Evolution of Lysis-Lysogeny Strategies Reproduces Observed Lysogeny Propensities in Temperate Bacteriophages

V Sinha, A Goyal, SL Svenningsen, S Semsey… - Frontiers in …, 2017 - frontiersin.org
Bacteriophages are the most abundant organisms on the planet and both lytic and
temperate phages play key roles as shapers of ecosystems and drivers of bacterial …

Models of life: epigenetics, diversity and cycles

K Sneppen - Reports on Progress in Physics, 2017 - iopscience.iop.org
This review emphasizes aspects of biology that can be understood through repeated
applications of simple causal rules. The selected topics include perspectives on gene …

Hitchhiking, collapse, and contingency in phage infections of migrating bacterial populations

D Ping, T Wang, DT Fraebel, S Maslov… - The ISME …, 2020 - academic.oup.com
Natural bacterial populations are subjected to constant predation pressure by
bacteriophages. Bacteria use a variety of molecular mechanisms to defend themselves from …

Bottom-up biofilm eradication using bacteriophage-loaded magnetic nanocomposites: a computational and experimental study

P Yu, Z Wang, M Marcos-Hernandez, P Zuo… - Environmental …, 2019 - pubs.rsc.org
Biofilms cause a variety of pervasive problems in water treatment, distribution and reuse
systems that are difficult to mitigate due to their resistance to disinfectants. We used …

Formation of phage lysis patterns and implications on co-propagation of phages and motile host bacteria

X Li, F Gonzalez, N Esteves, BE Scharf… - PLoS computational …, 2020 - journals.plos.org
Coexistence of bacteriophages, or phages, and their host bacteria plays an important role in
maintaining the microbial communities. In natural environments with limited nutrients, motile …

Phage susceptibility testing and infectious titer determination through wide-field lensless monitoring of phage plaque growth

P Perlemoine, PR Marcoux, E Picard, E Hadji… - Plos one, 2021 - journals.plos.org
The growing number of drug-resistant bacterial infections worldwide is driving renewed
interest in phage therapy. Based on the use of a personalized cocktail composed of highly …