Off-label use of medication may be presented in these guidelines if a sufficient level of
evidence shows that it can be considered medically appropriate to a given condition and if …

The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

Myocardial injury after noncardiac surgery is defined by elevated postoperative cardiac
troponin concentrations that exceed the 99th percentile of the upper reference limit of the …

As early as the 1920s, and subsequently in the 1959 Build and Blood Pressure Study (S1. 5-
1) of almost 5 million adults insured between 1934 and 1954, a strong direct relationship …

Aims The expression of GADD153 (growth arrest and DNA damage-inducible gene 153), an
apoptosis-regulated gene, increases during endoplasmic reticulum (ER) stress. How …

Importance Perioperative cardiovascular complications occur in 3% of hospitalizations for
noncardiac surgery in the US. This review summarizes evidence regarding cardiovascular …

Background Intraoperative hypotension is a common side effect of general anaesthesia and
might lead to inadequate organ perfusion. It is unclear to what extent hypotension during …

La tarea de elaboración de GPC incluye la creación de herramientas educativas y
programas de implementación de las recomendaciones. Para su implementación, se …

Background: Among patients having noncardiac surgery, perioperative hemodynamic
abnormalities are associated with vascular complications. Uncertainty remains about what …

Background The relative contributions of intraoperative and postoperative hypotension to
perioperative morbidity remain unclear. We determined the association between …