Two-component systems regulate bacterial virulence in response to the host gastrointestinal environment and metabolic cues

C Shaw, M Hess, BC Weimer - Virulence, 2022 - Taylor & Francis
Two-component systems are ubiquitous signaling mechanisms in bacteria that enable
intracellular changes from extracellular cues. These bacterial regulatory systems couple …

Microbial-derived tryptophan metabolites and their role in neurological disease: anthranilic acid and anthranilic acid derivatives

C Shaw, M Hess, BC Weimer - Microorganisms, 2023 - mdpi.com
The gut microbiome provides the host access to otherwise indigestible nutrients, which are
often further metabolized by the microbiome into bioactive components. The gut microbiome …

Pseudomonas syringae pv. tomato infection of tomato plants is mediated by GABA and l‐Pro chemoperception

S Santamaría‐Hernando… - Molecular plant …, 2022 - Wiley Online Library
Foliar bacterial pathogens have to penetrate the plant tissue and access the interior of the
apoplast in order to initiate the pathogenic phase. The entry process is driven by chemotaxis …

An atlas of bacterial two-component systems reveals function and plasticity in signal transduction

Y Xie, J Li, Y Ding, X Shao, Y Sun, F Xie, S Liu, S Tang… - Cell reports, 2022 - cell.com
Two-component systems (TCSs) consist of the biggest group of signal transduction
pathways in biology. Although TCSs play key roles in sensing signals to sustain survival and …

Ill Communication: host metabolites as virulence-regulating signals for plant-pathogenic bacteria

JC Anderson - Annual Review of Phytopathology, 2023 - annualreviews.org
Plant bacterial pathogens rely on host-derived signals to coordinate the deployment of
virulence factors required for infection. In this review, I describe how diverse plant …

The role of ATP-binding cassette transporters in bacterial phytopathogenesis

Y Zeng, AO Charkowski - Phytopathology®, 2021 - Am Phytopath Society
Bacteria use selective membrane transporting strategies to support cell survival in different
environments. Of the membrane transport systems, ATP-binding cassette (ABC) …

High temperatures promote antibiotic resistance genes conjugative transfer under residual chlorine: Mechanisms and risks

W Zhao, B Zhang, S Zheng, W Yan, X Yu… - Journal of Hazardous …, 2025 - Elsevier
The impact of residual chlorine on the dissemination of antibiotic resistance during the
distribution and storage of water has become a critical concern. However, the influence of …

Identification of Indole-3-Acetic Acid-Regulated Genes in Pseudomonas syringae pv. tomato Strain DC3000

AT Djami-Tchatchou, ZA Li, P Stodghill… - Journal of …, 2022 - Am Soc Microbiol
The auxin indole-3-acetic acid (IAA) is a plant hormone that not only regulates plant growth
and development but also plays important roles in plant-microbe interactions. We previously …

Transporter-mediated depletion of extracellular proline directly contributes to plant pattern-triggered immunity against a bacterial pathogen

CJ Rogan, YY Pang, SD Mathews, SE Turner… - Nature …, 2024 - nature.com
Plants possess cell surface-localized immune receptors that detect microbe-associated
molecular patterns (MAMPs) and initiate defenses that provide effective resistance against …

Regulation of Bacterial Growth and Behavior by Host Plant

S Nakagami, Z Wang, X Han… - Annual Review of …, 2024 - annualreviews.org
Plants are associated with diverse bacteria in nature. Some bacteria are pathogens that
decrease plant fitness, and others are beneficial bacteria that promote plant growth and …