Coronavirus infections and immune responses

G Li, Y Fan, Y Lai, T Han, Z Li, P Zhou… - Journal of medical …, 2020 - Wiley Online Library
Coronaviruses (CoVs) are by far the largest group of known positive‐sense RNA viruses
having an extensive range of natural hosts. In the past few decades, newly evolved …

Interferon-gamma-mediated osteoimmunology

M Tang, L Tian, G Luo, X Yu - Frontiers in immunology, 2018 - frontiersin.org
Osteoimmunology is the interdiscipline that focuses on the relationship between the skeletal
and immune systems. They are interconnected by shared signal pathways and cytokines …

Protective Role of γδ T Cells in Different Pathogen Infections and Its Potential Clinical Application

Y Zhao, L Lin, Z Xiao, M Li, X Wu, W Li… - Journal of …, 2018 - Wiley Online Library
γδ T cells, a subgroup of T cells based on the γδ TCR, when compared with conventional T
cells (αβ T cells), make up a very small proportion of T cells. However, its various subgroups …

γδ T‐cell responses during HIV infection and antiretroviral therapy

JA Juno, EM Eriksson - Clinical & translational immunology, 2019 - Wiley Online Library
HIV infection is associated with a rapid and sustained inversion of the Vδ1: Vδ2 T‐cell ratio
in peripheral blood. Studies of antiretroviral therapy (ART)‐treated cohorts suggest that ART …

Innate immune response against HPV: Possible crosstalking with endocervical γδ T cells

S Dogan, E Terzioglu, S Ucar - Journal of reproductive immunology, 2021 - Elsevier
Cervical carcinoma is significantly associated with the human papillomavirus (HPV).
Persistent infection with high risk-HPV is necessary but not sufficient for the development of …

Flagellin/NLRC4 pathway rescues NLRP3-inflammasome defect in dendritic cells from HIV-infected patients: perspective for new adjuvant in immunocompromised …

EC Reis, VNC Leal, JLS Soares… - Frontiers in …, 2019 - frontiersin.org
Introduction: NLRP3 inflammasome plays a key role in dendritic cells (DC) activation in
response to vaccine adjuvants, however we previously showed that it is not properly …

The role of polymorphonuclear neutrophils during HIV-1 infection

MM Yaseen, NM Abuharfeil, MM Yaseen… - Archives of …, 2018 - Springer
It is well-recognized that human immunodeficiency virus type-1 (HIV-1) mainly targets CD4+
T cells and macrophages. Nonetheless, during the past three decades, a huge number of …

Mucosal and systemic γδ+ T cells associated with control of simian immunodeficiency virus infection

I Tuero, D Venzon, M Robert-Guroff - The Journal of Immunology, 2016 - journals.aai.org
Abstract γδ T cells act as a first line of defense against invading pathogens. However,
despite their abundance in mucosal tissue, little information is available about their …

γδ T cells mediate robust anti‐HIV functions during antiretroviral therapy regardless of immune checkpoint expression

KR Field, KM Wragg, SJ Kent, WS Lee… - Clinical & …, 2024 - Wiley Online Library
Objectives Although antiretroviral therapy (ART) efficiently suppresses HIV viral load,
immune dysregulation and dysfunction persist in people living with HIV (PLWH). γδ T cells …

[HTML][HTML] Akkermansia muciniphila- and Pathogenic Bacteria-Derived Endotoxins Differently Regulate Human Dendritic Cell Generation and γδ T Lymphocyte …

V Fertitta, B Varano, M Del Cornò, P Fortini, A Aureli… - Biomolecules, 2024 - mdpi.com
Lipopolysaccharide (LPS) is a potent endotoxin released at high concentrations in acute
infections, causing massive host inflammatory response. Accumulating evidence indicates …