The cleavage of C–C bonds has been a great challenge owing to their thermodynamic and
kinetic stability. To date, the progress made in this area has mainly relied on the reaction of …

Abstract Carbon–carbon (C–C) bonds make up the skeletons of most organic molecules.
The selective manipulation of C–C bonds offers a direct approach to editing molecular …

Three-component carboacylation of simple alkenes with readily available reagents is
challenging. Transition metal-catalysed intermolecular carboacylation works for alkenes with …

The development of catalytic carboacylation of simple olefins, which would enable the rapid
construction of ketones with high levels of complexity and diversity, is very challenging. To …

C− C bond activation has emerged as an increasingly useful approach for constructing
complex molecular scaffolds through unusual bond-disconnection strategies. As a common …

The direct functionalization of C− H bonds is among the most fundamental chemical
transformations in organic synthesis. However, when the innate reactivity of the substrate …

A rhodium-catalyzed direct insertion of ethylene into a relatively unstrained carbon–carbon
bond in 1-indanones is reported, which provides a two-carbon ring expansion strategy for …

A silver-catalysed oxidative sp2 C–H alkylation of N-heteroarenes with ketone-derived 2, 3-
dihydroquinazolinones at room temperature is developed. The combination of a metal …

We have discovered chlorophyll catalyzed 1, 2-acyl migration reactions to achieve α-amino
carbonyl compounds directly from the enaminones. In general, singlet oxygen is generated …

A novel method for direct transformation of allyl groups in allylbenzene derivatives to alkenyl
groups via rhodium-catalyzed C–C bond cleavage is reported. The alkenylation with …