Alzheimer's disease (AD) is an aging-related neurological disorder characterized by
synaptic loss and dementia. Wnt/β-catenin signaling is an essential signal transduction …

Neurological diseases, particularly in the context of aging, have serious impacts on quality of
life and can negatively affect bone health. The brain-bone axis is critically important for …

Among the brainstem raphe nuclei, the dorsal raphe nucleus (DR) contains the greatest
number of Pet1-lineage neurons, a predominantly serotonergic group distributed throughout …

Alzheimer's disease (AD) poses an ever-increasing public health concern as the population
ages, affecting more than 6 million Americans. AD patients present with mood and sleep …

Intermittent fasting may be an effective intervention to protect against age-related metabolic
disturbances, although it is still controversial. Here, we investigated the effect of intermittent …

Inadequate osteogenesis and excessive adipogenesis of bone marrow mesenchymal stem
cells (BMSCs) are key factors in the pathogenesis of osteoporosis. Patients with Alzheimer's …

Abstract Purpose of Review This comprehensive review delves into the intricate interplay
between Alzheimer's disease (AD) and osteoporosis, two prevalent conditions with …

Hallmark features of Alzheimer's disease (AD) include elevated accumulation of aggregated
Aβ40 and Aβ42 peptides, hyperphosphorylated Tau (p-Tau), and neuroinflammation …

Abstract Purpose of Review This review examines the linked pathophysiology of Alzheimer's
disease/related dementia (AD/ADRD) and bone disorders like osteoporosis. The emphasis …

Osteoporosis and Alzheimer's disease (AD) are both degenerative diseases. Osteoporosis
often proceeds cognitive deficits, and multiple studies have revealed common triggers that …