Immunoglobulin (Ig) superfamily proteins play diverse roles in vertebrates, including
regulation of cellular responses by sensing endogenous or exogenous ligands. Siglecs are …

Dendritic cells (DCs) are principal defense components that play multifactorial roles in
translating innate immune responses to adaptive immunity in Mycobacterium tuberculosis …

Background Macrophages control innate and acquired immunity, but their role in severe
asthma remains ill‐defined. We investigated gene signatures of macrophage subtypes in the …

Tuberculosis (TB) remains a serious public health burden worldwide. TB is an infectious
disease caused by the Mycobacterium tuberculosis Complex. Innate immune response is …

Chronic obstructive pulmonary disease (COPD), characterized by chronic inflammation, is a
recognized global health crisis. Sialic acid-binding immunoglobulin-like lectin 1 (siglec1 or …

The identification of individuals with null alleles enables studying how the loss of gene
function affects infection. We previously described a non‐functional variant in SIGLEC1 …

We studied the prognostic value of SIGLEC1 in colorectal cancer (CRC) using
bioinformatics. SIGLEC1 exhibited differential expression between the tumor and control …

Host genetics are important to consider in the role of resistance or susceptibility for
developing active pulmonary tuberculosis (TB). Several association studies have reported …

Abstract Introduction: Between February and November 2016, 17 tuberculosis (TB) cases
were identified among high school students in Novi Pazar, Serbia. The objectives of our …

It has been documented that sialic acid-binding Ig-like lectin 1 (Siglec1) is a cell surface
protein with a variety of functions in the immune system. In the present study, we evaluated …