Epigenetic regulation of ageing: linking environmental inputs to genomic stability

BA Benayoun, EA Pollina, A Brunet - Nature reviews Molecular cell …, 2015 - nature.com
Ageing is affected by both genetic and non-genetic factors. Here, we review the chromatin-
based epigenetic changes that occur during ageing, the role of chromatin modifiers in …

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging

CA Mangold, B Wronowski, M Du, DR Masser… - Journal of …, 2017 - Springer
Background The necessity of including both males and females in molecular neuroscience
research is now well understood. However, there is relatively limited basic biological data on …

Sexual dimorphism in the response to dietary restriction in mice: A systematic review of the literature

SJ Mitchell, JR Mitchell - Nutrition and Healthy Aging, 2022 - content.iospress.com
Background: Dietary restriction (DR) is a widely used experimental intervention in aging
research due to its consistent ability to extend lifespan in most species tested. DR is an all …

Hippocampal extracellular matrix levels and stochasticity in synaptic protein expression increase with age and are associated with age-dependent cognitive decline

MJ Vegh, A Rausell, M Loos, CM Heldring… - Molecular & Cellular …, 2014 - ASBMB
Age-related cognitive decline is a serious health concern in our aging society. Decreased
cognitive function observed during healthy brain aging is most likely caused by changes in …

Disjunctive networks and update schedules

E Goles, M Noual - Advances in Applied Mathematics, 2012 - Elsevier
In this paper, we present a study of the dynamics of disjunctive networks under all block-
sequential update schedules. We also present an extension of this study to more general fair …

Do psychological sex differences reflect evolutionary bisexual partitioning?

I Trofimova - The American Journal of Psychology, 2015 - scholarlypublishingcollective.org
This article analyzes sex differences in communicative and exploratory abilities and mental
disabilities from the rarely discussed perspective of sex differences in the shape of …

On the effects of firing memory in the dynamics of conjunctive networks

E Goles, P Montealegre, M Ríos-Wilson - Cellular Automata and Discrete …, 2019 - Springer
Boolean networks are one of the most studied discrete models in the context of the study of
gene expression. In order to define the dynamics associated to a Boolean network, there are …

Effect of moxibustion on testosterone secretion and apoptosis of spermatogenic cells in aging rats

C Yao, C Zhao, S Zhang, S Liu - … ‐Based Complementary and …, 2019 - Wiley Online Library
Analysis of androgen secretion and sperm production was conducted in the testis to
investigate the efficacy of moxibustion on testicular function in aging rats. Male Sprague …

Gene expression, epigenetics and ageing

B Maniyadath, N Shukla… - Biochemistry and Cell …, 2018 - Springer
As the popular adage goes, all diseases run into old age and almost all physiological
changes are associated with alterations in gene expression, irrespective of whether they are …

Studying the Geroprotective Properties of YAP/TAZ Signaling Inhibitors on Drosophila melanogaster Model

DA Golubev, NV Zemskaya, AA Gorbunova… - International Journal of …, 2023 - mdpi.com
The transcriptional coactivators Yes-associated protein (YAP) and transcriptional coactivator
with PDZ-binding motif (TAZ) are the main downstream effectors of the evolutionarily …