The allergic airway diseases, including chronic rhinosinusitis (CRS), asthma, allergic
bronchopulmonary mycosis (ABPM) and many others, comprise a heterogeneous collection …

Proteinases and the innate immune receptor Toll-like receptor 4 (TLR4) are essential for
expression of allergic inflammation and diseases such as asthma. A mechanism that links …

Early life exposure to fine particulate matter (PM) in air is associated with infant respiratory
disease and childhood asthma, but limited epidemiological data exist concerning the …

Allergic asthma is a heterogeneous inflammatory lung disease affecting millions of people
worldwide and with a steadily increasing incidence. Mouse models have been of utmost …

Allergic asthma is a chronic inflammatory disease of the conducting airways characterized
by the presence of allergen‐specific IgE, Th2 cytokine production, eosinophilic airway …

Allergic asthma is a heterogeneous disorder that defies a unanimously acceptable
definition, but is generally recognized through its highly characteristic clinical expression of …

Rationale: Asthma is a chronic inflammatory disorder with a characteristic of airway
hyperresponsiveness (AHR). Ca2+-activated Cl−[Cl (Ca)] channels are inferred to be …

Background BALB/c and C57BL/6 mouse strains are commonly used in allergy research.
The current study investigated the immunological differences between these two mouse …

G protein-coupled receptors (GPCRs) are known to initiate a plethora of signaling pathways
in vitro. However, it is unclear which of these pathways are engaged to mediate …

Background The incidence of asthma is increasing at an alarming rate and while the current
available therapies are effective in the majority of patients they fail to adequately control …