The impact of medroxyprogesterone acetate on lipid profiles in Women: A time and dose-response meta-analysis of randomized controlled trials

L Feng, L Wang, B Hernández-Wolters… - Diabetes Research and …, 2024 - Elsevier
Background The effect of MPA on the lipid profile and CVD risk is still controversial; hence,
this comprehensive dose–response meta-analysis of randomized controlled trials was …

[HTML][HTML] Hormonal therapies in females with blood disorders: thrombophilia, thrombosis, hemoglobinopathies, and anemias

MK Baldwin, BS Bannow, RP Rosovsky… - Research and Practice …, 2023 - Elsevier
There is widespread use of gonadal steroid hormone therapy for a variety of indications
throughout the reproductive and postreproductive lifespan. These therapies may have …

Differential off-target glucocorticoid activity of progestins used in endocrine therapy

M Komane, C Avenant, R Louw-du Toit, DJ Africander… - Steroids, 2022 - Elsevier
The glucocorticoid receptor (GR) regulates transcription of genes involved in multiple
processes. Medroxyprogesterone acetate (MPA), widely used in the injectable contraceptive …

Safety of hormonal contraception for obese women

ALL Rocha, RR Campos, MMS Miranda… - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: Obese women have special safety requirements for contraceptive choice, but
the evidence supporting such decision is dispersed and sometimes conflicting. Despite …

Melatonin attenuates glucocorticoid effect induced by medroxyprogesterone acetate in rats

MM Andraschko, MT De Carvalho, HCM Pires… - General and …, 2022 - Elsevier
Medroxyprogesterone acetate (MPA) acts on glucocorticoid receptors and, when it is in
excess, can cause clinical disorders comparable to hyperadrenocorticism. Melatonin (MEL) …

Depot-medroxyprogesterone acetate: Lipid profile changes and associated cardiovascular risks among acceptors in Sagamu, South West Nigeria

O Odelola, A Akadri - Journal of Public Health in Africa, 2024 - pmc.ncbi.nlm.nih.gov
Depot-medroxyprogesterone acetate (DMPA) is a highly effective long acting reversible
contraceptive. Alterations in lipid profile have been associated with use of DMPA, however …

[HTML][HTML] Green Tea Extract has a Protective Effect on Leptin and Lipid Profile Levels Due to the Induction of Depot Medroxyprogesterone Acetate

ES Wahyuni, M Maryatun, N Veri, E Susilawati… - Medical …, 2023 - ncbi.nlm.nih.gov
Background: Depot medroxyprogesterone acetate (DMPA) is a progesterone derivative
synthesized in the laboratory. This substance has the ability to suppress ovulation, induce …

Effects of Various contraceptive methods on Clinical and Metabolic Parameters

M Abbasi - Archives of Medical Laboratory Sciences, 2019 - journals.sbmu.ac.ir
Background: Widespread usage of contraceptive pills and Medroxyprogesterone acetate
(Depo-Provera) as an injectable contraceptive can affect various biochemical and …

Ageing and women with bleeding disorders

S Radhakrishnan, R d'Oiron - The Journal of Haemophilia Practice, 2022 - sciendo.com
As life expectancy increases, women with bleeding disorders can expect to live for decades
after their menopause–potentially with a range of comorbidities including cardiovascular …

Subclinical cardiovascular disease parameters after one year in new users of depot medroxyprogesterone acetate compared to copper-IUD

K Cursino, GA de Lima… - … European Journal of …, 2018 - Taylor & Francis
Purpose: To evaluate markers of cardiovascular disease in women with normal insulin
sensitivity who had recently initiated use of depot medroxyprogesterone acetate (DMPA) as …