Microbes are ubiquitous in the natural environment of Caenorhabditis elegans. Bacteria
serve as a food source for C. elegans but may also cause infection in the nematode host …

A hallmark of adaptive behavior is the ability to flexibly respond to sensory cues. To
understand how neural circuits implement this flexibility, it is critical to resolve how a static …

Cryo-electron tomography (cryo-ET) is emerging as a revolutionary method for resolving the
structure of macromolecular complexes in situ. However, sample preparation for in situ Cryo …

Mitochondria are essential components of eukaryotic cells, carrying out critical physiological
processes that include energy production and calcium buffering. Consequently …

Caenorhabditis elegans' behavioral states, like those of other animals, are shaped by its
immediate environment, its past experiences, and by internal factors. We here review the …

Successful reproduction in animals requires orchestration of behavior and physiological
processes. Pheromones can induce both" releaser"(behavioral) and" priming"(physiological) …

Learning and memory are regulated by neuromodulatory pathways, but the contribution and
temporal requirement of most neuromodulators in a learning circuit are unknown. Here we …

Hydrogen peroxide is the preeminent chemical weapon that organisms use for combat.
Individual cells rely on conserved defenses to prevent and repair peroxide-induced damage …

Carbon dioxide (CO2) is an important sensory cue for many animals, including both parasitic
and free-living nematodes. Many nematodes show context-dependent, experience …

Diet profoundly affects metabolism and incidences of age-related diseases. Animals adapt
their physiology to different food-types, modulating complex life-history traits like aging. The …