Covering: 2015 up to 2022 (Feb) Silymarin, an extract of milk thistle (Silybum marianum)
fruits, has been used in various medicinal applications since ancient times. A major …

The extract from milk thistle (Silybum marianum (L.) Gaertn.(Asteraceae)), known as
silymarin, contains a variety of flavonolignans and displays antioxidant, anti-inflammatory …

Silymarin is an extract from the seeds (fruits) of Silybum marianum that contains
flavonolignans and flavonoids. Although it is frequently used as a hepatoprotective agent, its …

The critical function of dihydroorotate dehydrogenase (DHODH) in pyrimidine synthesis
attracted a great interest throughout beyond decades. Inhibitors of human DHODH …

This review focuses on the specific biological effects of optically pure silymarin flavo-
nolignans, mainly silybins A and B, isosilybins A and B, silychristins A and B, and their 2, 3 …

Multidrug resistance (MDR) is a major challenge for the 21th century in both cancer
chemotherapy and antibiotic treatment of bacterial infections. Efflux pumps and transport …

Herbal preparations from Silybum marianum have been used since the fourth century BC in
liver disease treatment and against numerous other pathologies. Consumption of silymarin …

Background Silymarin is a polyphenolic flavonoid complex extricated from dried fruits and
seeds of the plant Silybum marianum L. Chemically, it is a mixture of flavonolignan …

Numerous in vitro assays are used to characterize the antioxidant properties of natural-
based matrices. However, many of them generate contradictory and non-compliant results …

Antibiotic resistance is currently a serious health problem. Since the discovery of new
antibiotics no longer seems to be a sufficient tool in the fight against multidrug-resistant …