Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy

B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan, C Wu - Biomaterials, 2021 - Elsevier
Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …

Interplay of oxidative stress, cellular communication and signaling pathways in cancer

MJ Iqbal, A Kabeer, Z Abbas, HA Siddiqui… - Cell Communication and …, 2024 - Springer
Cancer remains a significant global public health concern, with increasing incidence and
mortality rates worldwide. Oxidative stress, characterized by the production of reactive …

The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

[HTML][HTML] Male infertility

SW Leslie, TL Soon-Sutton, MAB Khan - StatPearls [internet], 2024 - ncbi.nlm.nih.gov
Male Infertility - StatPearls - NCBI Bookshelf US flag An official website of the United States
government Here's how you know NIH NLM Logo Access keys NCBI Homepage MyNCBI …

[HTML][HTML] A systematic review on advances in management of oxidative stress-associated cardiovascular diseases

S Jin, PM Kang - Antioxidants, 2024 - mdpi.com
Oxidative stress plays a significant role in the pathogenesis of cardiovascular diseases, such
as myocardial ischemia/reperfusion injury, atherosclerosis, heart failure, and hypertension …

Dysbiosis of Gut Microbiota from the Perspective of the Gut–Brain Axis: Role in the Provocation of Neurological Disorders

M Kandpal, O Indari, B Baral, S Jakhmola, D Tiwari… - Metabolites, 2022 - mdpi.com
The gut–brain axis is a bidirectional communication network connecting the gastrointestinal
tract and central nervous system. The axis keeps track of gastrointestinal activities and …

Obesity-induced brain neuroinflammatory and mitochondrial changes

LO Schmitt, JM Gaspar - Metabolites, 2023 - mdpi.com
Obesity is defined as abnormal and excessive fat accumulation, and it is a risk factor for
developing metabolic and neurodegenerative diseases and cognitive deficits. Obesity is …

Mitochondrial, exosomal miR137-COX6A2 and gamma synchrony as biomarkers of parvalbumin interneurons, psychopathology, and neurocognition in schizophrenia

I Khadimallah, R Jenni, JH Cabungcal, M Cleusix… - Molecular …, 2022 - nature.com
Early detection and intervention in schizophrenia requires mechanism-based biomarkers
that capture neural circuitry dysfunction, allowing better patient stratification, monitoring of …

Introduction to traditional medicine and their role in prevention and treatment of emerging and re-emerging diseases

SAA Rizvi, GP Einstein, OL Tulp, F Sainvil, R Branly - Biomolecules, 2022 - mdpi.com
Infectious diseases have been a threat to human health globally. The relentless efforts and
research have enabled us to overcome most of the diseases through the use of antiviral and …

Therapeutic strategies to ameliorate neuronal damage in epilepsy by regulating oxidative stress, mitochondrial dysfunction, and neuroinflammation

S Madireddy, S Madireddy - Brain sciences, 2023 - mdpi.com
Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …