[HTML][HTML] Molecular insight into dengue virus pathogenesis and its implications for disease control

MS Diamond, TC Pierson - Cell, 2015 - cell.com
Dengue virus (DENV) is a mosquito-transmitted RNA virus that infects an estimated 390
million humans each year. Here, we review recent advances in our understanding of the …

Winning the tug-of-war between effector gene design and pathogen evolution in vector population replacement strategies

JM Marshall, RR Raban, NP Kandul, JR Edula… - Frontiers in …, 2019 - frontiersin.org
While efforts to control malaria with available tools have stagnated, and arbovirus outbreaks
persist around the globe, the advent of clustered regularly interspaced short palindromic …

Current Effector and Gene-Drive Developments to Engineer Arbovirus-Resistant Aedes aegypti (Diptera: Culicidae) for a Sustainable Population Replacement …

WR Reid, KE Olson, AWE Franz - Journal of Medical …, 2021 - academic.oup.com
Arthropod-borne viruses (arboviruses) such as dengue, Zika, and chikungunya viruses
cause morbidity and mortality among human populations living in the tropical regions of the …

Inhibition of dengue virus infection by small interfering RNAs that target highly conserved sequences in the NS4B or NS5 coding regions

PM Villegas, E Ortega, L Villa-Tanaca, BL Barrón… - Archives of …, 2018 - Springer
Dengue fever is one of the most common viral infections in the world. Although a vaccine
against dengue virus (DENV) has been approved in several countries, this disease is still …

Antiviral Effectors for Mosquito Transgenesis

AWE Franz - Transgenic Insects: Techniques and Applications, 2022 - cabidigitallibrary.org
Mosquito-transmitted arthropod-borne viruses ('arboviruses') such as the dengue viruses
(DENV 1-4), chikungunya virus (CHIKV), Zika virus (ZIKV), Japanese encephalitis virus …

Mating Competitiveness of Transgenic Aedes aegypti (Diptera: Culicidae) Males Against Wild-Type Males Reared Under Simulated Field Conditions

DS Kang, JM Cunningham, DD Lovin… - Journal of Medical …, 2020 - academic.oup.com
Efforts directed at genetic modification of mosquitoes for population control or replacement
are highly dependent on the initial mating success of transgenic male mosquitoes following …