Modern radiotherapy for head and neck cancer

D Alterio, G Marvaso, A Ferrari, S Volpe, R Orecchia… - Seminars in …, 2019 - Elsevier
Radiation therapy (RT) plays a key role in curative-intent treatments for head and neck
cancers. Its use is indicated as a sole therapy in early stage tumors or in combination with …

Intensity modulated proton therapy (IMPT)–The future of IMRT for head and neck cancer

AC Moreno, SJ Frank, AS Garden, DI Rosenthal… - Oral oncology, 2019 - Elsevier
Radiation therapy plays an integral role in the management of head and neck cancers
(HNCs). While most HNC patients have historically been treated with photon-based …

[HTML][HTML] Intensity-modulated proton beam therapy (IMPT) versus intensity-modulated photon therapy (IMRT) for patients with oropharynx cancer–a case matched …

P Blanchard, AS Garden, GB Gunn… - Radiotherapy and …, 2016 - Elsevier
Background Owing to its physical properties, intensity-modulated proton therapy (IMPT)
used for patients with oropharyngeal carcinoma has the ability to reduce the dose to organs …

Radiation resistance in head and neck squamous cell carcinoma: dire need for an appropriate sensitizer

MKND Hutchinson, M Mierzwa, NJ D'Silva - Oncogene, 2020 - nature.com
Radiation is a significant treatment for patients with head and neck cancer. Despite
advances to improve treatment, many tumors acquire radiation resistance resulting in poor …

Proton therapy for head and neck cancer: expanding the therapeutic window

JE Leeman, PB Romesser, Y Zhou, S McBride… - The lancet …, 2017 - thelancet.com
Use of proton beam therapy has expanded, with the number of proton centres rapidly
increasing not only in the USA but also worldwide. The physical characteristics of the proton …

Recent advances in radiation therapy and photodynamic therapy

LM Chong, DJH Tng, LLY Tan, MLK Chua… - Applied Physics …, 2021 - pubs.aip.org
In the past 100 years, external beam energy for the treatment of cancer has continually
evolved. Two main modes have been developed. The first is radiotherapy which involves …

Proton beam therapy for cancer in the era of precision medicine

M Hu, L Jiang, X Cui, J Zhang, J Yu - Journal of hematology & oncology, 2018 - Springer
Precision radiotherapy, which accurately delivers the dose on a tumor and confers little or no
irradiation to the surrounding normal tissue and organs, results in maximum tumor control …

Toward a model-based patient selection strategy for proton therapy: external validation of photon-derived normal tissue complication probability models in a head and …

P Blanchard, AJ Wong, GB Gunn, AS Garden… - Radiotherapy and …, 2016 - Elsevier
Objective To externally validate head and neck cancer (HNC) photon-derived normal tissue
complication probability (NTCP) models in patients treated with proton beam therapy (PBT) …

Proton therapy for head and neck cancers

P Blanchard, GB Gunn, A Lin, RL Foote, NY Lee… - Seminars in radiation …, 2018 - Elsevier
Because of its sharp lateral penumbra and steep distal fall-off, proton therapy offers
dosimetric advantages over photon therapy. In head and neck cancer, proton therapy has …

Proton therapy for squamous cell carcinoma of the head and neck: early clinical experience and current challenges

S Nuyts, H Bollen, SP Ng, J Corry, A Eisbruch… - Cancers, 2022 - mdpi.com
Simple Summary Proton therapy is a promising type of radiation therapy used to destroy
tumor cells. It has the potential to further improve the outcomes for patients with head and …