Anticancer activity of chitosan, chitosan derivatives, and their mechanism of action

HS Adhikari, PN Yadav - International Journal of Biomaterials, 2018 - Wiley Online Library
Tailoring of chitosan through the involvement of its amino, acetamido, and hydroxy groups
can give derivatives of enhanced solubility and remarkable anticancer activity. The general …

Intelligent poly (l-histidine)-based nanovehicles for controlled drug delivery

Y Zhang, I Kim, Y Lu, Y Xu, DG Yu, W Song - Journal of Controlled Release, 2022 - Elsevier
Stimuli-responsive drug delivery systems based on polymeric nanovehicles are among the
most promising treatment regimens for malignant cancers. Such intelligent systems that …

Nano drug delivery systems for antisense oligonucleotides (ASO) therapeutics

T Ramasamy, HB Ruttala, S Munusamy… - Journal of Controlled …, 2022 - Elsevier
Cancer, infectious diseases, and metabolic and hereditary genetic disorders are a global
health burden affecting millions of people, with contemporary treatments offering limited …

Smart chemistry-based nanosized drug delivery systems for systemic applications: a comprehensive review

T Ramasamy, HB Ruttala, B Gupta, BK Poudel… - Journal of Controlled …, 2017 - Elsevier
This review focuses on the smart chemistry that has been utilized in developing polymer-
based drug delivery systems over the past 10 years. We provide a comprehensive overview …

Nanomaterials loaded with Quercetin as an advanced tool for cancer treatment

C Caro, M Pourmadadi, MM Eshaghi… - Journal of Drug Delivery …, 2022 - Elsevier
Cancer is a major global problem ranking as the second/third cause of death, irrespective of
the region or the socio-economic situation. Quercetin (QCT), a flavonoid compound almost …

Injectable dual thermoreversible hydrogel for sustained intramuscular drug delivery

FU Din, JS Kim, HC Lee, S Cheon, MR Woo… - Journal of Controlled …, 2024 - Elsevier
Herein, we reported novel docetaxel-decorated solid lipid nanoparticle (DCT-SLN)-loaded
dual thermoreversible system (DCT-DRTS) for intramuscular administration with reduced …

α-Amino acid N-carboxyanhydride (NCA)-derived synthetic polypeptides for nucleic acids delivery

Y Liu, L Yin - Advanced Drug Delivery Reviews, 2021 - Elsevier
In recent years, gene therapy has come into the spotlight for the prevention and treatment of
a wide range of diseases. Polypeptides have been widely used in mediating nucleic acid …

Smart polymeric nanoparticles in cancer immunotherapy

Z Yu, X Shen, H Yu, H Tu, C Chittasupho, Y Zhao - Pharmaceutics, 2023 - mdpi.com
Cancer develops with unexpected mutations and causes death in many patients. Among the
different cancer treatment strategies, immunotherapy is promising with the benefits of high …

[HTML][HTML] Platelet-mimicking nanoparticles co-loaded with W18O49 and metformin alleviate tumor hypoxia for enhanced photodynamic therapy and photothermal …

H Zuo, J Tao, H Shi, J He, Z Zhou, C Zhang - Acta Biomaterialia, 2018 - Elsevier
W 18 O 49-mediated photodynamic therapy (PDT) and photothermal therapy (PTT) are
limited by the easily oxidized property and tumor hypoxia. Here, we report the development …

Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy

P Aiello, S Consalvi, G Poce, A Raguzzini, E Toti… - Seminars in Cancer …, 2021 - Elsevier
Application of nanotechnologies to cancer therapy might increase solubility and/or
bioavailability of bioactive compounds of natural or synthetic origin and offers other potential …