Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies

M Solmi, M De Toffol, JY Kim, MJ Choi, B Stubbs… - bmj, 2023 - bmj.com
Objective To systematically assess credibility and certainty of associations between
cannabis, cannabinoids, and cannabis based medicines and human health, from …

Therapeutic and clinical foundations of cannabidiol therapy for difficult-to-treat seizures in children and adults with refractory epilepsies

DS Reddy - Experimental neurology, 2023 - Elsevier
Novel and effective antiseizure medications are needed to treat refractory and rare forms of
epilepsy. Cannabinoids, which are obtained from the cannabis plant, have a long history of …

Pharmacological and therapeutic properties of cannabidiol for epilepsy

V Franco, E Perucca - Drugs, 2019 - Springer
Cannabidiol (CBD) is a major active component of the Cannabis plant, which, unlike
tetrahydrocannabinol (THC), is devoid of euphoria-inducing properties. During the last 10 …

[HTML][HTML] Exploration of Cannabis constituents as potential candidates against diabetes mellitus disease using molecular docking, dynamics simulations and ADMET …

O Abchir, O Daoui, H Nour, I Yamari, S Elkhattabi… - Scientific African, 2023 - Elsevier
Diabetes Mellitus is one of the deadliest diseases in the world, while the current medications
against this disease like acarbose represent many side effects such as diarrhea and …

Cannabidiol therapy for refractory epilepsy and seizure disorders

V Golub, DS Reddy - Cannabinoids and neuropsychiatric disorders, 2021 - Springer
Cannabis-derived cannabinoids have neuroactive properties. Recently, there has been
emerging interest in the use of cannabidiol (CBD)-enriched products for treatment of drug …

Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa

AR de Mello Schier… - CNS & Neurological …, 2014 - ingentaconnect.com
Anxiety and depression are pathologies that affect human beings in many aspects of life,
including social life, productivity and health. Cannabidiol (CBD) is a constituent non …

[HTML][HTML] Therapeutic approaches in Congenital Disorders of Glycosylation (CDG) involving N-linked glycosylation: an update

J Verheijen, S Tahata, T Kozicz, P Witters, E Morava - Genetics in Medicine, 2020 - Elsevier
Congenital disorders of glycosylation (CDG) are a group of clinically and genetically
heterogeneous metabolic disorders. Over 150 CDG types have been described. Most CDG …

Phytocannabinoid Pharmacology: Medicinal Properties of Cannabis sativa Constituents Aside from the “Big Two”

PB Sampson - Journal of Natural Products, 2020 - ACS Publications
Plant-based therapies date back centuries. Cannabis sativa is one such plant that was used
medicinally up until the early part of the 20th century. Although rich in diverse and interesting …

Use of cannabidiol for the treatment of anxiety: a short synthesis of pre-clinical and clinical evidence

M Wright, P Di Ciano, B Brands - Cannabis and cannabinoid …, 2020 - liebertpub.com
Anxiety disorders have the highest lifetime prevalence of any mental illness worldwide,
leading to high societal costs and economic burden. Current pharmacotherapies for anxiety …

Serious adverse effects of cannabidiol (CBD): a review of randomized controlled trials

RG Dos Santos, FS Guimarães… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Recent trials using cannabidiol (CBD) have shown that most acute and
prolonged adverse effects of CBD are mild to moderate, with rare serious adverse effects …