Emerging strategies to combat ESKAPE pathogens in the era of antimicrobial resistance: a review

MS Mulani, EE Kamble, SN Kumkar… - Frontiers in …, 2019 - frontiersin.org
The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …

The demand for new antibiotics: antimicrobial peptides, nanoparticles, and combinatorial therapies as future strategies in antibacterial agent design

A León-Buitimea, CR Garza-Cárdenas… - Frontiers in …, 2020 - frontiersin.org
The inappropriate use of antibiotics and an inadequate control of infections have led to the
emergence of resistant strains which represent a major threat to public health and the global …

The potential of antibiotics and nanomaterial combinations as therapeutic strategies in the management of multidrug-resistant infections: a review

OO Adeniji, N Nontongana, JC Okoh… - International journal of …, 2022 - mdpi.com
Antibiotic resistance has become a major public health concern around the world. This is
exacerbated by the non-discovery of novel drugs, the development of resistance …

Potential synergistic activity of quercetin with antibiotics against multidrug-resistant clinical strains of Pseudomonas aeruginosa

C Vipin, K Saptami, F Fida, M Mujeeburahiman… - PLoS one, 2020 - journals.plos.org
Development of drug resistance in opportunistic pathogens is one of the major healthcare
challenges associated with infection management. Combination therapy has many …

Bifunctional antimicrobial conjugates and hybrid antimicrobials

P Klahn, M Brönstrup - Natural product reports, 2017 - pubs.rsc.org
Covering: up to the end of 2016 Novel antimicrobial drugs are continuously needed to
counteract bacterial resistance development. An innovative molecular design strategy for …

Coping with the ESKAPE pathogens: Evolving strategies, challenges and future prospects

C Aloke, I Achilonu - Microbial pathogenesis, 2023 - Elsevier
Globally, the ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

Bromelain and nisin: The natural antimicrobials with high potential in biomedicine

U Jančič, S Gorgieva - Pharmaceutics, 2021 - mdpi.com
Infectious diseases along with various cancer types are among the most significant public
health problems and the leading cause of death worldwide. The situation has become even …

Role of medicinal plants from North Western Himalayas as an efflux pump inhibitor against MDR AcrAB-TolC Salmonella enterica serovar typhimurium: In vitro and In …

J Mehta, R Rolta, K Dev - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Zingiber officinale Roscoe has been utilized
traditionally to cure various diseases like cold, cough, diarrhoea, nausea, asthma, vomiting …

Nanotechnology: a contemporary therapeutic approach in combating infections from multidrug-resistant bacteria

B Brar, S Marwaha, AK Poonia, B Koul, S Kajla… - Archives of …, 2023 - Springer
In the 20th century, the discovery of antibiotics played an essential role in the fight against
infectious diseases, including meningitis, typhoid fever, pneumonia and Mycobacterium …

Nano-fats for bugs: The benefits of lipid nanoparticles for antimicrobial therapy

CR Thorn, N Thomas, BJ Boyd… - Drug Delivery and …, 2021 - Springer
Bacterial infections are an imminent global healthcare threat evolving from rapidly
advancing bacterial defence mechanisms that antibiotics fail to overcome. Antibiotics have …