Community-acquired bacterial meningitis

D van de Beek, M Brouwer, R Hasbun… - Nature reviews Disease …, 2016 - nature.com
Meningitis is an inflammation of the meninges and subarachnoid space that can also involve
the brain cortex and parenchyma. It can be acquired spontaneously in the community …

Community-acquired bacterial meningitis in adults in the Netherlands, 2006–14: a prospective cohort study

MW Bijlsma, MC Brouwer… - The Lancet infectious …, 2016 - thelancet.com
Background We studied causative pathogens, clinical characteristics, and outcome of adult
community-acquired bacterial meningitis after the introduction of adjunctive dexamethasone …

Recent Advances in Investigation, Prevention, and Management of Healthcare‐Associated Infections (HAIs): Resistant Multidrug Strain Colonization and Its Risk …

DC Zaha, R Kiss, C Hegedűs… - BioMed research …, 2019 - Wiley Online Library
Active screening for resistant multidrug strain carriers remains an important component of
infection control policy in any healthcare setting indifferent of financial and logistical costs …

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis

JA Lees, B Ferwerda, PHC Kremer, NE Wheeler… - Nature …, 2019 - nature.com
Streptococcus pneumoniae is a common nasopharyngeal colonizer, but can also cause life-
threatening invasive diseases such as empyema, bacteremia and meningitis. Genetic …

ZnO‐CuS/F127 Hydrogels with Multienzyme Properties for Implant‐Related Infection Therapy by Inhibiting Bacterial Arginine Biosynthesis and Promoting Tissue …

Y Sun, W Zhang, Z Luo, C Zhu, Y Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Implant‐related infections are characterized by the formation of bacterial biofilms. Current
treatments have various drawbacks. Nanozymes with enzyme‐like activity can produce …

Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model

KK Jim, JY Engelen-Lee, AM van der Sar… - Journal of …, 2016 - Springer
Background Streptococcus pneumoniae is one of the most important causes of bacterial
meningitis, an infection where unfavourable outcome is driven by bacterial and host-derived …

Regulation of the arginine deiminase system by ArgR2 interferes with arginine metabolism and fitness of Streptococcus pneumoniae

C Schulz, P Gierok, L Petruschka, M Lalk, U Mäder… - MBio, 2014 - Am Soc Microbiol
Streptococcus pneumoniae is auxotrophic for arginine, and molecular analysis of the
pneumococcal genome showed that the gene encoding an arginine-ornithine antiporter …

Prevalence and antibiotic resistance profiles of cerebrospinal fluid pathogens in children with acute bacterial meningitis in Yunnan province, China, 2012-2015

H Jiang, M Su, L Kui, H Huang, L Qiu, L Li, J Ma, T Du… - PloS one, 2017 - journals.plos.org
Acute bacterial meningitis is still considered one of the most dangerous infectious diseases
in children. To investigate the prevalence and antibiotic resistance profiles of cerebrospinal …

Dual RNA-seq in Streptococcus pneumoniae infection reveals compartmentalized neutrophil responses in lung and pleural space

ND Ritchie, TJ Evans - Msystems, 2019 - Am Soc Microbiol
Streptococcus pneumoniae is the dominant cause of community-acquired pneumonia
worldwide. Invasion of the pleural space is common and results in increased mortality. We …

Arginine metabolism powers Salmonella resistance to oxidative stress

A Margolis, L Liu, S Porwollik, JKA Till… - Infection and …, 2023 - Am Soc Microbiol
Salmonella invades host cells and replicates inside acidified, remodeled vacuoles that are
exposed to reactive oxygen species (ROS) generated by the innate immune response …