Transforming growth factor-β (TGF-β) induces a pleiotropic pathway that is modulated by the
cellular context and its integration with other signaling pathways. In cancer, the pleiotropic …

Transforming growth factor beta (TGF-β) is the most potent pro-fibrogenic cytokine and its
expression is increased in almost all of fibrotic diseases. Although signaling through Smad …

Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Reactive oxygen species (ROS) are generated as by-products of cellular metabolism,
primarily in the mitochondria. When cellular production of ROS overwhelms its antioxidant …

Transforming Growth Factor-beta in the Liver: Structure, Processing and Function 3. TGF-
beta Signal Transduction in Liver Cells 4. Hepatic Stellate Cell Activation 5. TGF-beta and …

Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …

Extracellular stimuli elicit a variety of responses, such as cell proliferation and differentiation,
through the cellular signalling system. Binding of growth factors to the respective receptor …

Transforming growth factor β (TGF-β) is the most potent and ubiquitous profibrogenic
cytokine, and its expression is increased in almost all the fibrotic diseases and in …

Transforming growth factor beta 1 (TGF beta) is a multifunctional cytokine that orchestrates
response to injury via ubiquitous cell surface receptors. The biological activity of TGF beta is …

The primary objective of this study was to determine the sequence of biochemical signaling
events that occur after modulation of the cellular redox state in the B cell lymphoma line, PW …