Review covering up to mid-2021 The structure of polyketide and non-ribosomal peptide natural products is strongly influenced by how they are released from their biosynthetic …
V Zickermann, C Wirth, H Nasiri, K Siegmund… - Science, 2015 - science.org
Proton-pumping complex I of the mitochondrial respiratory chain is among the largest and most complicated membrane protein complexes. The enzyme contributes substantially to …
NADH is a key metabolic cofactor whose sensitive and specific detection in the cytosol of live cells has been difficult. We constructed a fluorescent biosensor of the cytosolic NADH …
DJ Becker, JB Lowe - Glycobiology, 2003 - academic.oup.com
Fucose is a deoxyhexose that is present in a wide variety of organisms. In mammals, fucose- containing glycans have important roles in blood transfusion reactions, selectin-mediated …
Aromatic aldehydes are useful in numerous applications, especially as flavors, fragrances, and pharmaceutical precursors. However, microbial synthesis of aldehydes is hindered by …
JL Ferrer, MB Austin, C Stewart Jr, JP Noel - Plant Physiology and …, 2008 - Elsevier
As a major component of plant specialized metabolism, phenylpropanoid biosynthetic pathways provide anthocyanins for pigmentation, flavonoids such as flavones for protection …
KL Kavanagh, H Jörnvall, B Persson… - Cellular and Molecular …, 2008 - Springer
Short-chain dehydrogenases/reductases (SDRs) constitute a large family of NAD (P)(H)- dependent oxidoreductases, sharing sequence motifs and displaying similar mechanisms …
JW Tomlinson, EA Walker, IJ Bujalska… - Endocrine …, 2004 - academic.oup.com
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) interconverts inactive cortisone and active cortisol. Although bidirectional, in vivo it is believed to function as a reductase …
ST Krause, P Liao, C Crocoll… - Proceedings of the …, 2021 - National Acad Sciences
Thymol and carvacrol are phenolic monoterpenes found in thyme, oregano, and several other species of the Lamiaceae. Long valued for their smell and taste, these substances also …