Abscisic acid biosynthesis and catabolism

E Nambara, A Marion-Poll - Annu. Rev. Plant Biol., 2005 - annualreviews.org
The level of abscisic acid (ABA abscisic acid) in any particular tissue in a plant is determined
by the rate of biosynthesis and catabolism of the hormone. Therefore, identifying all the …

Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis

RF Little, C Hertweck - Natural Product Reports, 2022 - pubs.rsc.org
Review covering up to mid-2021 The structure of polyketide and non-ribosomal peptide
natural products is strongly influenced by how they are released from their biosynthetic …

Mechanistic insight from the crystal structure of mitochondrial complex I

V Zickermann, C Wirth, H Nasiri, K Siegmund… - Science, 2015 - science.org
Proton-pumping complex I of the mitochondrial respiratory chain is among the largest and
most complicated membrane protein complexes. The enzyme contributes substantially to …

Imaging cytosolic NADH-NAD+ redox state with a genetically encoded fluorescent biosensor

YP Hung, JG Albeck, M Tantama, G Yellen - Cell metabolism, 2011 - cell.com
NADH is a key metabolic cofactor whose sensitive and specific detection in the cytosol of
live cells has been difficult. We constructed a fluorescent biosensor of the cytosolic NADH …

Fucose: biosynthesis and biological function in mammals

DJ Becker, JB Lowe - Glycobiology, 2003 - academic.oup.com
Fucose is a deoxyhexose that is present in a wide variety of organisms. In mammals, fucose-
containing glycans have important roles in blood transfusion reactions, selectin-mediated …

Synthesis and Accumulation of Aromatic Aldehydes in an Engineered Strain of Escherichia coli

AM Kunjapur, Y Tarasova… - Journal of the American …, 2014 - ACS Publications
Aromatic aldehydes are useful in numerous applications, especially as flavors, fragrances,
and pharmaceutical precursors. However, microbial synthesis of aldehydes is hindered by …

Structure and function of enzymes involved in the biosynthesis of phenylpropanoids

JL Ferrer, MB Austin, C Stewart Jr, JP Noel - Plant Physiology and …, 2008 - Elsevier
As a major component of plant specialized metabolism, phenylpropanoid biosynthetic
pathways provide anthocyanins for pigmentation, flavonoids such as flavones for protection …

Medium-and short-chain dehydrogenase/reductase gene and protein families: the SDR superfamily: functional and structural diversity within a family of metabolic and …

KL Kavanagh, H Jörnvall, B Persson… - Cellular and Molecular …, 2008 - Springer
Short-chain dehydrogenases/reductases (SDRs) constitute a large family of NAD (P)(H)-
dependent oxidoreductases, sharing sequence motifs and displaying similar mechanisms …

11β-Hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response

JW Tomlinson, EA Walker, IJ Bujalska… - Endocrine …, 2004 - academic.oup.com
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) interconverts inactive cortisone and
active cortisol. Although bidirectional, in vivo it is believed to function as a reductase …

The biosynthesis of thymol, carvacrol, and thymohydroquinone in Lamiaceae proceeds via cytochrome P450s and a short-chain dehydrogenase

ST Krause, P Liao, C Crocoll… - Proceedings of the …, 2021 - National Acad Sciences
Thymol and carvacrol are phenolic monoterpenes found in thyme, oregano, and several
other species of the Lamiaceae. Long valued for their smell and taste, these substances also …