Telomere shortening is a well-known hallmark of both cellular senescence and organismal
aging. An accelerated rate of telomere attrition is also a common feature of age-related …

Telomere attrition is associated with increased morbidity and mortality of various age-related
diseases. Reports of association between telomere length (TL) and all-cause mortality …

Cellular senescence describes an irreversible growth arrest characterized by distinct
morphology, gene expression pattern, and secretory phenotype. The final or intermediate …

Telomeres are nucleoprotein caps flanking DNA. They are shortened by cell division and
oxidative stress and are lengthened by the enzyme telomerase and DNA exchange during …

To determine the most important drivers of successful ageing at extreme old age, we
combined community-based prospective cohorts: Tokyo Oldest Old Survey on Total Health …

OBJECTIVE: To provide a systematic review of the relationship between age and leukocyte
telomere length (LTL) in adults. METHODS: Relevant studies were identified by a systematic …

Maintaining the high standards that made the previous editions such well-respected and
widely used references, Food Lipids: Chemistry, Nutrition, and Biotechnology, Fourth Edition …

Telomeres, the DNA–protein structures located at the ends of chromosomes, have been
proposed to act as a biomarker of aging. In this review, the human evidence that telomere …

Asthma in older people is common and is characterised by underdiagnosis and
undertreatment. Ageing is associated with unique issues that modify expression …

Background. Leukocyte telomere length (LTL) is related to diseases of aging, but studies of
mortality have been inconsistent. Methods. We evaluated LTL in relation to total mortality …