Discovery of immune molecules and their crucial functions in shrimp immunity

A Tassanakajon, K Somboonwiwat, P Supungul… - Fish & shellfish …, 2013 - Elsevier
Several immune-related molecules in penaeid shrimps have been discovered, most of these
via the analysis of expressed sequence tag libraries, microarray studies and proteomic …

Structural biology of the LPS recognition

R Jerala - International Journal of Medical Microbiology, 2007 - Elsevier
Bacterial endotoxin (lipopolysaccharide–LPS) as one of the most potent inducers of the
immune system is recognized by a complex cascade of extracellular “pattern recognition …

Antibiotic polymyxin arranges lipopolysaccharide into crystalline structures to solidify the bacterial membrane

S Manioglu, SM Modaresi, N Ritzmann, J Thoma… - Nature …, 2022 - nature.com
Polymyxins are last-resort antibiotics with potent activity against multi-drug resistant
pathogens. They interact with lipopolysaccharide (LPS) in bacterial membranes, but …

[HTML][HTML] An intimate link between antimicrobial peptide sequence diversity and binding to essential components of bacterial membranes

P Schmitt, RD Rosa, D Destoumieux-Garzón - Biochimica et biophysica …, 2016 - Elsevier
Antimicrobial peptides and proteins (AMPs) are widespread in the living kingdom. They are
key effectors of defense reactions and mediators of competitions between organisms. They …

Interactions of lipopolysaccharide and polymyxin studied by NMR spectroscopy

J Mares, S Kumaran, M Gobbo, O Zerbe - Journal of Biological Chemistry, 2009 - ASBMB
In the light of occurrence of bacterial strains with multiple resistances against most
antibiotics, antimicrobial peptides that interact with the outer layer of Gram-negative bacteria …

Designed β-Boomerang Antiendotoxic and Antimicrobial Peptides: STRUCTURES AND ACTIVITIES IN LIPOPOLYSACCHARIDE*♦

A Bhunia, H Mohanram, PN Domadia, J Torres… - Journal of Biological …, 2009 - ASBMB
Lipopolysaccharide (LPS), an integral part of the outer membrane of Gram-negative
bacteria, is involved in a variety of biological processes including inflammation, septic shock …

Multifunctional host defense peptides: functional and mechanistic insights from NMR structures of potent antimicrobial peptides

S Bhattacharjya, A Ramamoorthy - The FEBS journal, 2009 - Wiley Online Library
The ever‐increasing number of drug‐resistant bacteria is a major challenge in healthcare
and creates an urgent need for novel compounds for treatment. Host defense antimicrobial …

Anti-lipopolysaccharide factors from the black tiger shrimp, Penaeus monodon, are encoded by two genomic loci

S Tharntada, K Somboonwiwat… - Fish & shellfish …, 2008 - Elsevier
Different isoforms of the ALF homologues (ALFPm1–5) have been previously identified from
Penaeus monodon expressed sequence tag (EST) database (http://pmonodon. biotec. or …

De novo designed lipopolysaccharide binding peptides: structure based development of antiendotoxic and antimicrobial drugs

S Bhattacharjya - Current medicinal chemistry, 2010 - ingentaconnect.com
Lipopolysaccharide (LPS), the glycolipid of the outer membrane of Gram-negative bacteria,
is critically involved in health and diseases. LPS facilitates the survival of pathogens by …

A new group of anti-lipopolysaccharide factors from Marsupenaeus japonicus functions in antibacterial response

HS Jiang, Q Zhang, YR Zhao, WM Jia, XF Zhao… - Developmental & …, 2015 - Elsevier
Anti-lipopolysaccharide factors (ALFs) are a group of critical effector molecules with a broad
spectrum of antimicrobial activities in crustaceans. Four groups of ALFs (A, B, C, and D) …