Design and application of fluorescent probes to detect cellular physical microenvironments

J Ma, R Sun, K Xia, Q Xia, Y Liu, X Zhang - Chemical Reviews, 2024 - ACS Publications
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …

Ratiometric two-photon fluorescence probes for sensing, imaging and biomedicine applications at living cell and small animal levels

H Jin, M Yang, Z Sun, R Gui - Coordination Chemistry Reviews, 2021 - Elsevier
The unique two-photon excitable luminescence and dual-emission ratio output features
endow organic molecule-based ratiometric two-photon fluorescence (RTPF) probes as …

Ratiometric fluorescent probes for pH mapping in cellular organelles

S Munan, R Yadav, N Pareek, A Samanta - Analyst, 2023 - pubs.rsc.org
The intracellular pH (pHi) in organelles, including mitochondria, endoplasmic reticulum,
lysosomes, and nuclei, differs from the cytoplasmic pH, and thus maintaining the pH of these …

Small two-photon organic fluorogenic probes: sensing and bioimaging of cancer relevant biomarkers

AK Singh, AV Nair, NDP Singh - Analytical chemistry, 2021 - ACS Publications
Fluorescence imaging is considered one of the most versatile methods to detect and trace
substances in living systems, owing to its unique advantages such as simplicity, high …

Recent Advances in small molecule‐based intracellular ph probes

PE Hande, YG Shelke, A Datta, SJ Gharpure - ChemBioChem, 2022 - Wiley Online Library
Intracellular pH plays an important role in many biological and pathological processes.
Small‐molecule based pH probes are found to be the most effective for pH sensing because …

Advances in small-molecule fluorescent probes for the study of apoptosis

YX Ye, JC Pan, HC Wang, XT Zhang, HL Zhu… - Chemical Society …, 2024 - pubs.rsc.org
Apoptosis, as type I cell death, is an active death process strictly controlled by multiple
genes, and plays a significant role in regulating various activities. Mounting research …

N and S doped carbon dots as novel probes with fluorescence enhancement for fast and sensitive detection of Cr (VI)

Y Chen, H Cui, M Wang, X Yang, S Pang - Colloids and Surfaces A …, 2022 - Elsevier
Cr (VI) is a toxic heavy metal, which is not readily decomposed and ingested by bacteria.
Therefore, there is an urgent need for a sensing method with high selectivity and high …

A pH-sensitive carbonic anhydrase Ⅸ-targeted near-infrared probe for fluorescent sensing and imaging of hypoxic osteosarcoma

Z Hu, R Li, X Cui, C Hu, Z Chen - Sensors and Actuators B: Chemical, 2023 - Elsevier
Osteosarcoma (OS) is the most prevalent carcinoma of the skeletal system with high rate of
mortality and morbidity. The rate of limb salvage and overall survival for patients with …

Monitoring the pH fluctuation of lysosome under cell stress using a near-infrared ratiometric fluorescent probe

L Gui, K Wang, Y Wang, J Yan, X Liu, J Guo, J Liu… - Chinese Chemical …, 2023 - Elsevier
Cell stress responses are associated with numerous diseases including diabetes,
neurodegenerative diseases, and cancer. Several events occur under cell stress, in which …

Evaluating the tumor stratification with a lysosomal pH sensitive-probe by fluorescence lifetime imaging

J Yan, X Liang, Q Zhang, L Wang, W Lin - Chinese Chemical Letters, 2024 - Elsevier
Owing to the anaerobic metabolism in the tumor, abundant acidic metabolites are produced
and accumulated in the cells. Therefore, the cells in different tumor layers are directly linked …