Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease

H Zhang, Y Wang, Y Wang, X Li, S Wang… - European Journal of …, 2022 - Elsevier
Abstract Alzheimer's disease (AD), as the fourth leading cause of death among the elderly
worldwide, has brought enormous challenge to the society. Due to its extremely complex …

Structure-based virtual screening, molecular docking, and molecular dynamics simulation of VEGF inhibitors for the clinical treatment of ovarian cancer

S Mukherjee, M Abdalla, M Yadav, M Madhavi… - Journal of Molecular …, 2022 - Springer
Vascular endothelial growth factor (VEGF) and its receptor play an important role both in
physiologic and pathologic angiogenesis, which is identified in ovarian cancer progression …

Structure-based virtual screening, molecular docking, molecular dynamics simulation and pharmacokinetic modelling of cyclooxygenase-2 (COX-2) inhibitor for the …

M Yadav, M Abdalla, M Madhavi, I Chopra… - Molecular …, 2022 - Taylor & Francis
Colorectal cancer is the third most frequent cause of cancer worldwide and is more
prevalent in older individuals of all ages. The recent statistics from World Health …

[PDF][PDF] Phytoconstituents of zingiber officinale targeting host-viral protein interaction at entry point of sars-COV-2: A molecular docking study

AS Chakotiya, RK Sharma - Defence Life Science Journal, 2020 - researchgate.net
Current COVID 19 outbreak is a critical issue in safeguarding public health worldwide. The
lack of prophylactic drugs, vaccine and effective antiviral and other supporting therapies has …

Synthesis, crystal structure, hirshfeld surface analysis, molecular docking and molecular dynamics studies of novel olanzapinium 2, 5-dihydroxybenzoate as potential …

V Natchimuthu, M Abdalla, M Yadav… - Journal of …, 2022 - Taylor & Francis
The antipsychotic drug Olanzapine was crystallized with aromatic acid, 2, 5-
dihydroxybenzoic acid in isopropyl alcohol by slow evaporation which led to the formation of …

Structural insights into conformational stability of ESR1 and structure base screening of new potent inhibitor for the treatment of Breast Cancer

I Chopra, U Panwar, A Bhrdwaj, M Madhavi, L Soni… - 2022 - researchsquare.com
Estrogen receptor alpha (ERα), a nuclear receptor protein encoded by the estrogen
receptor1 (ESR1) gene, is an important biomarker in breast cancer diagnosis. Any …

[PDF][PDF] Synthesis and structure analysis of methyl 1-benzyl-5-(phenylamino) methyl)-1H-1, 2, 3-triazole-4-carboxylate.

GY Erdemir, A Altundas - Organic Communications, 2023 - acgpubs.org
Azole motifs are commonly found in the pharmaceutical industry both as in commercial
products and in the literature. In particular, the triazole motifs have many applications such …