Fused bicyclic 1, 2, 4‐triazoles with one extra sulfur atom: Synthesis, properties, and biological activity

MV Slivka, NI Korol, MM Fizer - Journal of Heterocyclic …, 2020 - Wiley Online Library
Abstract Fused heterocyclic systems with 1, 2, 4‐triazole scaffold arouse great interest from
researchers in the branch of heterocyclic and medical chemistry because of their wide …

The use of electrophilic cyclization for the preparation of condensed heterocycles

M Slivka, M Onysko - Synthesis, 2021 - thieme-connect.com
Condensed heterocycles are well-known for their excellent biological effects and they are
undeniably important compounds in organic chemistry. Electrophilic cyclization reactions …

Halo-heterocyclization of butenyl(prenyl)thioethers of 4,5-diphenyl-1,2,4-triazol-3-thiole into triazolo[5,1-b] [1,3]thiazinium systems: experimental and theoretical …

N Korol, M Slivka, M Fizer, V Baumer… - Monatshefte für Chemie …, 2020 - Springer
A facile and highly efficient regioselective synthesis of partially saturated triazolo [5, 1-b][1, 3]
thiazinium salts by the electrophilic heterocyclization of the butenyl thioethers of 4, 5 …

Visible-light-mediated regioselective synthesis of novel thiazolo [3, 2-b][1, 2, 4] triazoles: advantageous synthetic application of aqueous conditions

R Aggarwal, M Hooda, P Kumar… - Organic & Biomolecular …, 2022 - pubs.rsc.org
From a green chemistry perspective, sustainable irradiation as the power source and water
as the solvent have certainly grabbed the attention of chemists in recent times because their …

[1,3]Thiazolo[3,2-b][1,2,4]triazol-7-ium salts: synthesis, properties and structural studies

M Slivka, N Korol, M Fizer, V Baumer… - Heterocyclic …, 2018 - degruyter.com
Abstract The reactions of [1, 3] thiazolo [3, 2-b][1, 2, 4] triazol-7-ium salts with nucleophiles
were investigated. Theoretical investigation of reactivity descriptors and structural …

Recent Development in the Synthesis of Thiazoles

DX Duc, NT Chung - Current Organic Synthesis, 2022 - ingentaconnect.com
Background: Thiazole-containing compounds are widely found in natural products as well
as synthetic sources. Many thiazole-based compounds possess a broad spectrum of …

Synthesis, Biological Evaluation and Molecular Docking Studies of Novel Series of Bis-1, 2, 4-Triazoles as Thymidine Phosphorylase Inhibitor

N Korol, OM Holovko-Kamoshenkova… - … and Applications in …, 2023 - Taylor & Francis
Introduction Heterocyclic compounds have diverse biological activities and potential in drug
development. This study aims to synthesize novel compounds with two 1, 2, 4-triazole cores …

Synthesis and Antimicrobial Activity of Functional Derivatives of thiazolo [2, 3-c][1, 2, 4] triazoles

M Slivka, M Fizer, R Mariychuk… - Letters in Drug …, 2022 - ingentaconnect.com
Background: Condensed triazoles are a well-known class of heterocyclic compounds due to
a wide range of biological activities. The study is dedicated to the evaluation of the …

Peculiarities of 4-methallyl-5-methallylamino-1, 2, 4-triazole-3-thione halogenation

MM Fizer, MV Slivka, VG Lendel - Chemistry of Heterocyclic Compounds, 2019 - Springer
Bromination and iodination of 4-methallyl-5-methallylamino-1, 2, 4-triazole-3-thione lead to
the annulation of five-and six-membered thiazaheterocycles, respectively. The usage of …

Palladium-Catalysed Intermolecular Direct C–H Bond Arylation of Heteroarenes with Reagents Alternative to Aryl Halides: Current State of the Art

R Rossi, M Ciofalo - Current Organic Chemistry, 2022 - ingentaconnect.com
This unprecedented review with 322 references provides a critical up-to-date picture of the
Pd-catalysed intermolecular direct C–H bond arylation of heteroarenes with arylating …