Traumatic brain injury (TBI) is a heterogeneous disorder that involves brain damage due to
external forces. TBI is the main factor of death and morbidity in young males with a high …

With the continuous development of immunotherapy, researchers have paid more attention
to the specific immune regulatory mechanisms of various immune responses in different …

Traumatic brain injury (TBI) can lead to significant neuropsychiatric problems and
neurodegenerative pathologies, which develop and persist years after injury …

Innate DNA sensing via the cyclic GMP-AMP synthase–stimulator of interferon genes (cGAS–
STING) mechanism surveys microbial invasion and cellular damage and thus participates in …

Stimulator of interferons genes (STING), which is crucial for the secretion of type I interferons
and proinflammatory cytokines in response to cytosolic nucleic acids, plays a key role in the …

The cGAS–STING pathway is an evolutionarily conserved immune signaling pathway critical
for microbial defense. Unlike other innate immune pathways that largely rely on stationary …

Given the unprecedented global pandemic of obesity, a better understanding of the etiology
of adiposity will be necessary to ensure effective management of obesity and related …

Traumatic brain injury (TBI) is associated with high mortality and disability, with a substantial
socioeconomic burden. With the standardization of the treatment process, there is increasing …

Traumatic brain injury (TBI) is associated with an increased risk of cognitive, psychiatric, and
neurodegenerative complications that may develop after injury. Increased microglial …

The anti-viral pattern recognition receptor STING and its partnering cytosolic DNA sensor
cGAS have been increasingly recognized to respond to self DNA in multiple pathologic …